Encapsulated thrombolytic microspheres to prevent reocclusion after thrombolysis and triggered release microspheres to deliver therapeutic drugs
H Nguyen - 2015 - shareok.org
Cardiovascular diseases, including acute myocardial infarction, stroke, peripheral arterial
diseases, and pulmonary embolism, are the most common and growing cause of morbidity …
diseases, and pulmonary embolism, are the most common and growing cause of morbidity …
An In Vitro Thrombolysis Study Using a Mixture of Fast-Acting and Slower Release Microspheres
HX Nguyen, EA O'Rear - Pharmaceutical research, 2016 - Springer
Purpose To test the hypothesis that a mixture combining fast and slower release rate
microspheres can restore blood flow rapidly and prevent formation of another blockage in …
microspheres can restore blood flow rapidly and prevent formation of another blockage in …
Biphasic release of protein from polyethylene glycol and polyethylene glycol/modified dextran microspheres
HX Nguyen, EA O'Rear - Journal of Biomedical Materials …, 2013 - Wiley Online Library
Dextrans show great promise for delivery of therapeutic agents. Dextran acetates (DAs)
were synthesized with increasing degrees of substitution (DA1< DA2< DA3) by the reaction …
were synthesized with increasing degrees of substitution (DA1< DA2< DA3) by the reaction …
Particles for Targeted Delivery and Uses in Managing Bleeding or Blood Clotting
US20230330031A1 - Particles for Targeted Delivery and Uses in Managing Bleeding or Blood
Clotting - Google Patents US20230330031A1 - Particles for Targeted Delivery and Uses in …
Clotting - Google Patents US20230330031A1 - Particles for Targeted Delivery and Uses in …
[HTML][HTML] Bio-inspired microcapsule for targeted antithrombotic drug delivery
W Ye, N Wang, K Hu, L Zhang, A Liu, C Pan, T Gong… - RSC …, 2018 - pubs.rsc.org
Thrombosis or embolism is the leading cause of death and long-term adult disability
worldwide. To reduce the risk of thrombosis and hemorrhaging in patients, a facile and …
worldwide. To reduce the risk of thrombosis and hemorrhaging in patients, a facile and …
Reducing the Side Effects of Thrombolytic Agent by Regulating its Release Rate from Microcapsules
L Mukhametova, R Aisina, K Gerchkovich… - …, 2019 - thieme-connect.com
Methods: PEG microcapsules containing SK were prepared by the method of double
emulsification, using an ultrasonic device and polyvinyl alcohol as emulsifying agent. To …
emulsification, using an ultrasonic device and polyvinyl alcohol as emulsifying agent. To …
Thrombolytic microspheres to dissolve vaso-occlusive clots
RCK Yen - US Patent App. 17/208,736, 2021 - Google Patents
A product, composition, suspension and/or method to treat subjects infected with respiratory
viruses, such as coronavirus, and in relieving hypoxic condition. A suspension of …
viruses, such as coronavirus, and in relieving hypoxic condition. A suspension of …
Drug delivery under cover of erythrocytes extends drug half-life: A thrombolytic targeting therapy utilizing microenvironment-responsive artificial polysaccharide …
L Shan, J Wang, H Tu, W Zhang, H Li, P Slezak… - Carbohydrate …, 2024 - Elsevier
The development of thrombolytic drug carriers capable of thrombus-targeting, prolonged
circulation time, intelligent responsive release, and the ability to inhibit thrombotic …
circulation time, intelligent responsive release, and the ability to inhibit thrombotic …
Modified dextran, heparin-based triggered release microspheres for cardiovascular delivery of therapeutic drugs using protamine as a stimulus
HX Nguyen, EA O'Rear - Journal of Microencapsulation, 2017 - Taylor & Francis
In this study, we describe the synthesis of an amine-modified acetalated dextran polymer,
which is combined with heparin (HP) as the basis for a novel controlled release system …
which is combined with heparin (HP) as the basis for a novel controlled release system …
Particles for targeted delivery and uses in managing bleeding or blood clotting
This disclosure relates to microcapsule particles for targeted delivery of drugs. In certain
embodiments, the particles comprise polyelectrolyte polymers, eg, layers of anionic …
embodiments, the particles comprise polyelectrolyte polymers, eg, layers of anionic …