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(54) METHODS AND COMPOSITIONS FOR 6,410,517 B1 6/2002 Truong et a1. TARGETED
DELIVERY OF THERAPEUTIC 6,652,873 B2 11/2003 Deareretal AGENTS 7,060,291 Bl …

0001. This application is a continuation-in-part of US application Ser. No. 09/703,474 filed
Oct. 31, 2000, which is a continuation-in-part of US application Ser. No. 09/478, 124, filed …

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(54) METHODS AND COMPOSITIONS FOR 5/0636 (2013.01); C12N5/0647 (2013.01);
LOCALIZED AGENT DELVERY CI2N 15/87 (2013.01); A61K 2035/124 (2013.01)(75) …

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The present invention relates to a method of targeting an agent towards a targeting site in a
tissue comprising admin istering a multi-specific antibody or antibody fragment com prising a …

Amethod of treating a speci? c site in a mammal With a drug comprises (a) providing a
carrier material Which re? ects or absorbs or emits electromagnetic or mechanical vibrations …

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