Pathophysiological integration of metabolic reprogramming in breast cancer

R Corchado-Cobos, N García-Sancha… - Cancers, 2022 - mdpi.com
Simple Summary Tumors exhibit metabolic changes that differentiate them from the normal
tissues from which they derive. These metabolic changes favor tumor growth, are primarily …

Breast cancer cell subtypes display different metabolic phenotypes that correlate with their clinical classification

C Ripoll, M Roldan, MJ Ruedas-Rama, A Orte… - Biology, 2021 - mdpi.com
Simple Summary Recent studies on cancer cell metabolism have achieved notable
breakthroughs that have led to a new scientific paradigm. How cancer cell metabolic …

[HTML][HTML] Metabolic crosstalk in the breast cancer microenvironment

AS Dias, CR Almeida, LA Helguero, IF Duarte - European Journal of …, 2019 - Elsevier
During tumorigenesis, breast tumour cells undergo metabolic reprogramming, which
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …

Differences in metabolic programming define the site of breast cancer cell metastasis

H Döppler, P Storz - Cell Metabolism, 2015 - cell.com
Although metabolic reprogramming is a hallmark of oncogenic transformation and growth of
primary tumor cells, little is known about how metabolic alterations impact metastasis. In this …

[HTML][HTML] On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer

J Penkert, T Ripperger, M Schieck, B Schlegelberger… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Altered metabolism in tumor cells has been a focus of cancer research for as long as a
century but has remained controversial and vague due to an inhomogeneous overall …

Metabolic implication of tumor: stroma crosstalk in breast cancer

A Morandi, P Chiarugi - Journal of molecular medicine, 2014 - Springer
The metabolic properties of cancer cells significantly differ from those of normal cells. In
particular, cancer cells are largely dependent on aerobic glycolysis, a phenomenon that has …

Cancer cell metabolism: one hallmark, many faces

JR Cantor, DM Sabatini - Cancer discovery, 2012 - AACR
Cancer cells must rewire cellular metabolism to satisfy the demands of growth and
proliferation. Although many of the metabolic alterations are largely similar to those in …

Metabolic codependencies in the tumor microenvironment

P Dey, AC Kimmelman, RA DePinho - Cancer Discovery, 2021 - AACR
Metabolic reprogramming enables cancer cell growth, proliferation, and survival. This
reprogramming is driven by the combined actions of oncogenic alterations in cancer cells …

Shifting the gears of metabolic plasticity to drive cell state transitions in cancer

Z Wu, YF Lee, XH Yeo, SY Loo, WL Tam - Cancers, 2021 - mdpi.com
Simple Summary Metabolic adaptation by cancer cells is enabled through the rewiring of
metabolic processes, thereby allowing them to survive and thrive in diverse tissue …

[HTML][HTML] Metabolic codependencies in the tumor microenvironment and gastric cancer: difficulties and opportunities

X Zhao, K Li, M Chen, L Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Oncogenesis and the development of tumors affect metabolism throughout the body.
Metabolic reprogramming (also known as metabolic remodeling) is a feature of malignant …