HIV drug resistance in children and adolescents: always a challenge?

WLA Koay, J Kose-Otieno, N Rakhmanina - Current epidemiology reports, 2021 - Springer
Abstract Purpose of Review With the expanded roll-out of antiretrovirals for treatment and
prevention of HIV during the last decade, the emergence of HIV drug resistance (HIVDR) …

Transmitted HIV-1 drug resistance among young men of color who have sex with men: a multicenter cohort analysis

LB Hightow-Weidman, CB Hurt, G Phillips II… - Journal of Adolescent …, 2011 - Elsevier
BACKGROUND: Given the elevated potential for primary or transmitted drug resistance
(TDR) among newly HIV-infected individuals, there is a need for a deeper understanding of …

HIV drug resistance in mothers and infants following use of antiretrovirals to prevent mother-to-child transmission

Q Ton, L Frenkel - Current HIV research, 2013 - ingentaconnect.com
The purpose of this article is to review prominent studies on HIV drug-resistance in mothers
and their infants after the use of antiretroviral drugs to prevent mother-to-child-transmission …

Implications of HIV drug resistance on first-and second-line therapies in resource-limited settings: report from a workshop organized by the Collaborative HIV and Anti …

D Pillay, J Albert, S Bertagnolio, C Boucher… - Antiviral …, 2013 - journals.sagepub.com
Here, we summarize the discussions and conclusions from an expert workshop held in
October 2012 to consider the implications of HIV drug resistance in the context of scale-up of …

Prevalence and risk factors associated with antiretroviral resistance in HIV‐1‐infected children

C Delaugerre, J Warszawski, ML Chaix… - Journal of medical …, 2007 - Wiley Online Library
In the USA and West Europe, nearly 80% of HIV‐1‐infected adults, experiencing virologic
failure, harbored virus strain resistant to at least one antiretroviral drug. Limited data are …

HIV drug resistance in infants increases with changing prevention of mother-to-child transmission regimens

LK Poppe, C Chunda-Liyoka, EH Kwon, C Gondwe… - Aids, 2017 - journals.lww.com
Objectives: The objectives of this study were to determine HIV drug resistance (HIVDR)
prevalence in Zambian infants upon diagnosis, and to determine how changing prevention …

Global HIV antiretroviral drug resistance: a perspective and report of a national institute of allergy and infectious diseases consultation

C Godfrey, MC Thigpen, KW Crawford… - The Journal of …, 2017 - academic.oup.com
Antiretroviral therapy (ART) is recommended for all people infected with human
immunodeficiency virus (HIV). The importance of wide population coverage and effective …

HIV transmission and primary drug resistance.

D Turner, MA Wainberg - AIDS reviews, 2006 - europepmc.org
Transmission of HIV viruses harboring resistance mutations is already a major concern in
developed countries, with the potential to impact on therapeutic strategies. Several factors …

Impact of human immunodeficiency virus drug resistance on treatment of human immunodeficiency virus infection in children in low-and middle-income countries

GK Siberry, A Amzel, A Ramos… - The Journal of …, 2017 - academic.oup.com
Children living with human immunodeficiency virus (HIV) in low-and middle-income
countries (LMICs) experience higher rates of virologic failure than adults. Human …

Drug resistance among adolescents and young adults with virologic failure of first-line antiretroviral therapy and response to second-line treatment

V Kouamou, B Varyani, T Shamu… - AIDS research and …, 2020 - liebertpub.com
Barriers to sustainable virologic suppression (VS) of HIV-infected adolescents and young
adults include drug resistance mutations (DRMs) and limited treatment options, which may …