The phytoalexin resveratrol has been described to have chemopreventive and
chemotherapeutic effects in several tumor models while its effects on osteosarcoma have …

Chondrosarcoma is a malignant primary bone tumor. Sirtuin-1 (SIRT1), which is a member
of sirtuin family, plays a dual role either in cancer promotion or suppression. There is no …

Purpose SIRT1-activating compounds (STACs) may have potential in the management of
cancer. However, the best-studied STAC, the naturally occurring compound resveratrol, is …

Purpose To investigate resveratrol (RSV) as a calorie restriction (CR) mimetic potentiator of
platinum-based cancer drugs. Methods In ovarian carcinoma cell lines, the potentiating …

Resveratrol prolongs lifespan and prevent cancer formation; however, the mechanisms are
not understood. Here we evaluated the cell-cycle inhibition and apoptosis of resveratrol in …

Sirt1 is a NAD+-dependent protein-modifying enzyme involved in regulating gene
expression, DNA damage repair, metabolism and survival, as well as acts as an important …

The currently available chemotherapeutic regimens against gastric cancer are not very
effective, leading to high recurrence and poor survival. Resveratrol is a naturally occurring …

Resveratrol produces substantial metabolic benefits in rodent models, and there have been
positive indications in several small human trials, yet the mechanism of action for this …

Abstract Resveratrol (RSV), a plant‐derived stilbene, induces cell death in Hodgkin
lymphoma (HL)‐derived L‐428 cells in a dose‐dependent manner (IC50= 27 μM, trypan …

The phytochemical resveratrol has recently gained attention for its protection against
metabolic disease and for extension of life span, which have been linked to its metabolic …