SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells

Y Cheng, L Cai, P Jiang, J Wang, C Gao, H Feng… - European journal of …, 2013 - Elsevier
Melatonin, the main secretory product of the pineal gland, has potent antitumor activity
against various types of cancer. However, the molecular mechanisms underlying the effects …

[HTML][HTML] In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFκB signaling in pancreatic cancer cells

JJ Duan, W Yue, JY E, J Malhotra, S Lu, J Gu, F Xu… - Scientific reports, 2016 - nature.com
Resveratrol (RES) has been studied extensively as an anticancer agent. However, the
anticancer effects of triacetylresveratrol (TRES, an acetylated analog of RES) which has …

[HTML][HTML] Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent

J Fu, A Shrivastava… - International …, 2019 - spandidos-publications.com
Abstract Trans‑3, 4', 5‑trihydroxystilbene (resveratrol) is a naturally occurring polyphenolic
phytoalexin with marked anticancer activities, and is mainly found in grapes, berries and …

Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells

E Madan, S Prasad, P Roy, J George… - … and biophysical research …, 2008 - Elsevier
Resveratrol (trans-3, 4′, 5-trihydroxystilbene), a polyphenolic phytoalexin present mainly in
grapes, red wine and berries, is known to possess strong chemopreventive and anticancer …

Dual effects of resveratrol on cell death and proliferation of colon cancer cells

Á San Hipólito-Luengo, A Alcaide… - Nutrition and …, 2017 - Taylor & Francis
Colorectal cancer remains a main cause of deaths worldwide, and novel agents are being
searched to treat this disease. Polyphenols have emerged as promising therapeutic tools in …

[HTML][HTML] Resveratrol inhibits proliferation and induces autophagy by blocking SREBP1 expression in oral cancer cells

M Fukuda, Y Ogasawara, H Hayashi, K Inoue… - Molecules, 2022 - mdpi.com
Resveratrol is a polyphenolic antioxidant found in grapes, red wine, and peanuts and has
been reported to have anti-neoplastic effects on various cancer types. However, the exact …

Resveratrol as an anticancer nutrient: molecular basis, open questions and promises

P Signorelli, R Ghidoni - The Journal of nutritional biochemistry, 2005 - Elsevier
The polyphenol resveratrol is an anticancer nutrient that was shown to inhibit cancer
initiation and promotion [Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW …

Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells

SH Baek, JH Ko, H Lee, J Jung, M Kong, J Lee, J Lee… - Phytomedicine, 2016 - Elsevier
Background Signal transducer and activator of transcription 3 (STAT3) is persistently
activated in squamous cell carcinoma of the head and neck (SCCHN) and can cause …

Resveratrol Derivative, Trans‐3, 5, 4 ‐Trimethoxystilbene Sensitizes Osteosarcoma Cells to Apoptosis via ROS‐Induced Caspases Activation

Y Feng, J Clayton, W Yake, J Li, W Wang… - Oxidative Medicine …, 2021 - Wiley Online Library
Numerous studies have shown that resveratrol can induce apoptosis in cancer cells. Trans‐
3, 5, 4′‐trimethoxystilbene (TMS), a novel derivative of resveratrol, is a more potent …

[HTML][HTML] Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer

T Taniguchi, Y Iizumi, M Watanabe, M Masuda… - Cell death & …, 2016 - nature.com
Resveratrol has various attractive bioactivities, such as prevention of cancer,
neurodegenerative disorders, and obesity-related diseases. Therefore, identifying its direct …