Resveratrol Derivative, Trans‐3, 5, 4 ‐Trimethoxystilbene Sensitizes Osteosarcoma Cells to Apoptosis via ROS‐Induced Caspases Activation

Y Feng, J Clayton, W Yake, J Li, W Wang… - Oxidative Medicine …, 2021 - Wiley Online Library
Numerous studies have shown that resveratrol can induce apoptosis in cancer cells. Trans‐
3, 5, 4′‐trimethoxystilbene (TMS), a novel derivative of resveratrol, is a more potent …

Inhibition of cell transformation by resveratrol and its derivatives: differential effects and mechanisms involved

QB She, WY Ma, M Wang, A Kaji, CT Ho, Z Dong - Oncogene, 2003 - nature.com
Resveratrol, a constituent of grapes and other foods, has been reported to be a potential
cancer chemopreventive agent. Our previous study showed that the antitumor activity of …

SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway

DW Wang, ZM Hu, J Hao, B He, Q Gan, XM Zhong… - Age, 2013 - Springer
Many studies have demonstrated that SIRT1, an NAD+-dependent deacetylase, reduces
apoptosis in several different cells. However, the role of SIRT1 in apoptosis of disc nucleus …

Taming the beast within: resveratrol suppresses colitis and prevents colon cancer

LJ Hofseth, UP Singh, NP Singh, M Nagarkatti… - Aging (Albany …, 2010 - ncbi.nlm.nih.gov
SIRT-1 is involved in colitis, functioning as an inverse regulator of NF-κB activation and
inflammation. Furthermore, our results indicated that resveratrol may protect against colitis …

Resveratrol is neuroprotective because it is not a direct activator of Sirt1—A hypothesis

BL Tang - Brain research bulletin, 2010 - Elsevier
The plant polyphenol resveratrol (3, 5, 4′-trihydroxystilbene) has been touted to have
multiple health benefits. A commonly cited mechanism of resveratrol action is via the …

Chemosensitization of tumors by resveratrol

SC Gupta, R Kannappan, S Reuter… - Annals of the New …, 2011 - Wiley Online Library
Because tumors develop resistance to chemotherapeutic agents, the cancer research
community continues to search for effective chemosensitizers. One promising possibility is to …

Different antioxidative and antiapoptotic effects of piceatannol and resveratrol

R Hosoda, H Hamada, D Uesugi, N Iwahara… - … of Pharmacology and …, 2021 - ASPET
Resveratrol affords protection against reactive oxygen species (ROS)-related diseases via
activation of SIRT1, an NAD+-dependent deacetylase. However, the low bioavailability of …

[HTML][HTML] Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: modulation of the phosphoinositide 3-kinase pathway

DA Benitez, E Pozo-Guisado, M Clementi… - British journal of …, 2007 - nature.com
Prostate cancer represents a major concern in human oncology and the phytoalexin
resveratrol (RES) inhibits growth and proliferation of prostate cancer cells through the …

[HTML][HTML] The Anticancer Effect of a Flavonoid-Rich Extract of Bergamot Juice in THP-1 Cells Engages the SIRT2/AKT/p53 Pathway

A Maugeri, C Russo, L Musumeci, GE Lombardo… - Pharmaceutics, 2022 - mdpi.com
Novel targets are constantly sought to fight hematologic malignancies. In this regard, high
levels of SIRT2 expression are associated with unfavorable prognosis of acute myeloid …

Resveratrol and it's effects Resveratrol ve etkileri

A Bay Karabulut - Turkiye Klinikleri Journal of Medical Sciences, 2008 - avesis.aybu.edu.tr
Resveratrol is produced by plants (skin of the red grapes peanuts, raspberries, mulberries,
blueberries, cranberries) in response to injury or fungal infection. It also protects plants from …