Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis
PJ Little, A Chait, A Bobik - Pharmacology & therapeutics, 2011 - Elsevier
Cardiovascular disease is the largest cause of morbidity and premature mortality and its
major underlying pathology is atherosclerosis. Atherosclerosis commences with the …
major underlying pathology is atherosclerosis. Atherosclerosis commences with the …
[HTML][HTML] Molecular and cellular mechanisms of inflammation in atherosclerosis
NM Popa-Fotea, CE Ferdoschi… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis and its complications are a major cause of morbidity and mortality worldwide
in spite of the improved medical and invasive treatment in terms of revascularization …
in spite of the improved medical and invasive treatment in terms of revascularization …
Inflammatory related cardiovascular diseases: from molecular mechanisms to therapeutic targets
Inflammation is a pathogenic response to multiple factors, that causes over-activation of
different molecules and pro-inflammatory cellular lines. Different behavioral factors and risk …
different molecules and pro-inflammatory cellular lines. Different behavioral factors and risk …
[HTML][HTML] Critical roles of inflammation in atherosclerosis
J Moriya - Journal of cardiology, 2019 - Elsevier
There is accumulating evidence that vascular inflammation plays critical roles in
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
[HTML][HTML] The impact of cytokines in coronary atherosclerotic plaque: current therapeutic approaches
Coronary atherosclerosis is a chronic pathological process that involves inflammation
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …
together with endothelial dysfunction and lipoprotein dysregulation. Experimental studies …
Novel anti-inflammatory therapies for the treatment of atherosclerosis
R Khan, V Spagnoli, JC Tardif, PL L'Allier - Atherosclerosis, 2015 - Elsevier
The underlying role of inflammation in atherosclerosis has been characterized. However,
current treatment of coronary artery disease (CAD) predominantly consists of targeted …
current treatment of coronary artery disease (CAD) predominantly consists of targeted …
[HTML][HTML] Inflammation and atherosclerosis: signaling pathways and therapeutic intervention
P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …
Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies
R Klingenberg, GK Hansson - European heart journal, 2009 - academic.oup.com
Atherosclerosis constitutes the underlying disease to the clinical manifestations of
myocardial infarction, stroke, and gangrene. Despite the success of statins, prevention of …
myocardial infarction, stroke, and gangrene. Despite the success of statins, prevention of …
[HTML][HTML] Inflammation in coronary atherosclerosis: insights into pathogenesis and therapeutic potential of anti-inflammatory drugs
CS Figueiredo, ES Roseira, TT Viana, MAD Silveira… - Pharmaceuticals, 2023 - mdpi.com
Atherosclerosis is a lipid-driven immune-inflammatory disease that affects the arteries,
leading to multifocal plaque development. The inflammatory process involves the activation …
leading to multifocal plaque development. The inflammatory process involves the activation …
Tackling inflammation in atherosclerosis: Are we there yet and what lies beyond?
P Bhattacharya, R Kanagasooriyan… - Current Opinion in …, 2022 - Elsevier
Atherosclerosis is a lipid-driven disease of the artery characterized by chronic non-resolving
inflammation. Despite availability of excellent lipid-lowering therapies, atherosclerosis …
inflammation. Despite availability of excellent lipid-lowering therapies, atherosclerosis …