Anti-inflammatory add-on therapy to conventional cardiovascular prophylaxis has been
proposed as a novel therapeutic approach to potentially reduce residual cardiovascular risk …

Despite advances in prevention and treatment, atherosclerotic vascular disease continues to
account for significant morbidity, mortality, and economic burden in the western world. Our …

Atherosclerosis is believed to be a chronic inflammation of the arterial wall and various
immune cells of innate and adaptive immunity involves in the pathogenesis of …

The recognition of atherogenesis as an active process rather than a passive cholesterol
storage disease has underlined key inflammatory mechanisms. Hence, innate and adaptive …

In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

Coronary artery disease (CAD) and acute myocardial infarction (AMI) are inflammatory
pathologies, involving interleukins (ILs), such as IL-1β, IL-6 and tumor necrosis factor (TNF) …

Evidence suggests that inflammation plays an important role in atherosclerosis and the
consequent clinical presentation, including stable coronary artery disease (CAD) and acute …

Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

For more than 20 years, our understanding of the biology of atherosclerosis has
incorporated the so-called inflammatory hypothesis. 1, 2 Inflammatory cells and signals drive …

Atherosclerotic cardiovascular disease is a leading cause of death and morbidity globally.
Over the past several years, arterial inflammation has been implicated in the …