Inflammatory cytokines and cardiovascular disease

T Ito, U Ikeda - Current Drug Targets-Inflammation & Allergy, 2003 - ingentaconnect.com
The designation of atherosclerosis as a chronic inflammatory process represents an
interesting paradigmatic shift for cardiologists. The plasma concentrations of interleukin-6 …

Inflammation modulation and cardiovascular disease prevention

Z Awan, J Genest - European Journal of Preventive Cardiology, 2015 - academic.oup.com
Heart disease and stroke represent the major burden of health worldwide and account for a
staggering 17 million deaths yearly. This pandemic is, in great part preventable through …

Inflammation and cardiovascular diseases: lessons from seminal clinical trials

L Liberale, F Montecucco, L Schwarz… - Cardiovascular …, 2021 - academic.oup.com
Inflammation has been long regarded as a key contributor to atherosclerosis. Inflammatory
cells and soluble mediators play critical roles throughout arterial plaque development and …

Combating inflammation in cardiovascular disease

AM Sethwala, I Goh, JV Amerena - Heart, Lung and Circulation, 2021 - Elsevier
The role of inflammation in promoting atherosclerosis and subsequent cardiovascular
disease is increasingly recognised, particularly after the publication of Anti-inflammatory …

Recent advances on the role of cytokines in atherosclerosis

H Ait-Oufella, S Taleb, Z Mallat… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …

Inflammation in coronary atherosclerosis and its therapeutic implications

NJ Montarello, MT Nguyen, DTL Wong… - … drugs and therapy, 2022 - Springer
Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …

Inflammation in coronary artery disease and acute myocardial infarction-is the stage set for novel therapies?

R Klingenberg, TF Luscher - Current pharmaceutical design, 2012 - ingentaconnect.com
Acute myocardial infarction (AMI) constitutes the major cause of death in most nations and
death rates and morbidity remain substantial in the years thereafter. Inflammation is a …

Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Targeting the residual cardiovascular risk by specific anti-inflammatory interventions as a therapeutic strategy in atherosclerosis

A Hafiane, SS Daskalopoulou - Pharmacological Research, 2022 - Elsevier
Chronic subclinical inflammation is a key process in the pathogenesis of atherosclerotic
cardiovascular disease (ASCVD). Along with lipids, inflammation is essential for the initiation …

The utility of anti-inflammatory agents in cardiovascular disease: a novel perspective on the treatment of atherosclerosis

SJ Kottoor, RR Arora - Journal of cardiovascular …, 2018 - journals.sagepub.com
Approximately 40% of heart attack survivors remain at increased risk of recurrent
cardiovascular events, despite the current treatment options showing that atherothrombosis …