Atherosclerosis is a pathological process caused by vascular remodeling. It symbolizes one
of the major causes for morbidity and mortality in the western world. The causes for these …

More than 150 years from the initial description of inflammation in atherosclerotic plaques,
randomized clinical trials to test anti-inflammatory therapies in atherosclerosis have recently …

Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

It is now widely accepted that the development of atherosclerotic lesions involves a chronic
inflammatory response that includes both innate and adaptive immune mechanisms …

Data from basic science experiments is overwhelmingly supportive of the causal role of
immune‐inflammatory response (s) at the core of atherosclerosis, and therefore, the …

The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …

Atherosclerosis contributes to the development of many cardiovascular diseases, which
remain the leading cause of death in developed countries. Atherosclerosis is a chronic …

Aims Targeting vascular inflammation represents a novel therapeutic approach to reduce
complications of atherosclerosis. Neutralizing the pro-inflammatory cytokine interleukin-1β …

Atherosclerosis is a chronic inflammatory process and both the innate and adaptive immune
systems 1 play central roles in its initiation and subsequent progression. 2 Experimental …

Inflammation contributes to all phases of the atherothrombotic process, patients with
elevated inflammatory biomarkers such as high-sensitivity C-reactive protein (hsCRP) have …