Pityriacitrin is a natural marine alkaloid with a typical β-carboline scaffold, and which has
been demonstrated to exhibit diverse biological functions. The special structural features for …

We report herein the chemical synthesis and biological evaluation of β-carboline alkaloid
pityriacitrin and some of its new derivatives. Using tryptophan or 5-hydroxytryptophan and 5 …

Pityriacitrin is a marine alkaloid with typical β-carboline scaffold, and which has been proven
to exhibit diverse biological functions. During the course of our research for highly active …

Pyrrole-imidazole alkaloids (PIAs) constitute a highly diverse and densely functionalized
subclass of marine natural products. Among them, the uncommon dimeric PIAs with ornate …

Oroidin derived pyrrole imidazole marine alkaloids (PIAs) are attractive targets for synthetic
organic chemists because of their structural complexity and diversity as well as their …

Pyridoacridine alkaloids, distributed in marine organisms have emerged as an important
class of compounds due to their uniqure chemical architecture, diversity and medicinal …

Marine bis-indole alkaloids comprise a large and increasingly growing class of secondary
metabolites, and continue to deliver a great variety of structural templates for diverse …

Previous studies indicated the marine pyridoacridone alkaloid ascididemin possessed a
unique biological profile. Investigation of synthetic routes to ascididemin led to the discovery …

Secondary metabolites from marine organisms are a rich source of novel leads for drug
development. Among these natural products, polycyclic aromatic alkaloids of the …

Marine organisms produce numerous secondary metabolites that exhibit a wide range of
biological activities, which have applications in pharmaceutical research. Numerous …