Fluoride-induced iron overload contributes to hepatic oxidative damage in mouse and the protective role of grape seed proanthocyanidin extract

Q Niu, P He, S Xu, R Ma, Y Ding, L Mu… - The Journal of …, 2018 - jstage.jst.go.jp
Emerging evidence has demonstrated that iron overload plays an important role in oxidative
stress in the liver. This study aimed to explore whether fluoride-induced hepatic oxidative …

[PDF][PDF] Effect of fluoride toxicity on some clinical, biochemical and physiological aspects of albino rats

S Arpita, B Bidyut - International Journal of Research in Chemistry …, 2012 - researchgate.net
Fluorine is a necessary biological trace element for human health. However, fluoride
accumulation leads to cascading effects resulting in altered physiological functions in …

Role of oxidative stress-mediated cell death and signaling pathways in experimental fluorosis

S Babu, S Manoharan, H Ottappilakkil… - Chemico-Biological …, 2022 - Elsevier
Free radicals and other oxidants have enticed the interest of researchers in the fields of
biology and medicine, owing to their role in several pathophysiological conditions, including …

[PDF][PDF] Recovery from fluoride and aluminium induced free radical liver toxicity in mice

N Chinoy, A Sharma, T Patel, R Memon, D Jhala - Fluoride, 2004 - researchgate.net
Adult male Swiss strain albino mice (Mus musculus) were administered orally sodium
fluoride (NaF, 10 mg/kg bw), aluminium chloride (AlCl3, 200 mg/kg bw), or both together for …

In vitro evaluation of the apoptotic, autophagic, and necrotic molecular pathways of fluoride

F Urut, S Dede, V Yuksek, S Çetin, A Usta… - Biological trace element …, 2021 - Springer
Prolonged exposure to high doses of fluoride causes chronic poisoning called fluorosis,
which affects many tissues and causes serious health problems. This study was planned to …

Toxicity of sodium fluoride in liver of albino rat and the beneficial effect of calcium in reversing fluoride toxicity: histological, ultrastructural and immunohistochemical …

AS Sewelam - The Egyptian Journal of Hospital Medicine, 2017 - journals.ekb.eg
Background: fluoride (F) is an essential element for human being from health point of view.
Its intake in high doses caused toxic effects on various organs. The liver is a target organ for …

Liver proteome of mice with different genetic susceptibilities to the effects of fluoride

ZN Khan, AL Leite, S Charone, IT Sabino… - Journal of Applied Oral …, 2016 - SciELO Brasil
ABSTRACT A/J and 129P3/J mice strains have been widely studied over the last few years
because they respond quite differently to fluoride (F) exposure. 129P3/J mice are …

[PDF][PDF] Toxicity of fluoride in liver of Albino rat and Mitigation after adopting artificial (Vitamin C and D) and natural (Aloe vera) food supplementations

S Parihar, A Choudhary, S Gaur - IJoART, 2013 - academia.edu
Fluoride is a widespread non biodegradable and relatively persistent pollutant, which at low
levels of contamination causes serious health problems difficult to cure. Fluoride pollution in …

Drp1/Mff signaling pathway is involved in fluoride-induced abnormal fission of hepatocyte mitochondria in mice

B Zhou, S Wei, L Jia, Y Zhang, C Miao… - Science of The Total …, 2020 - Elsevier
Fluoride, a toxic substance, is widely distributed in the environment and causes serious
damage to the body. This study was performed to investigate the effects of fluoride on …

Evaluation of fluoride-induced oxidative stress in rat brain: a multigeneration study

PM Basha, P Rai, S Begum - Biological trace element research, 2011 - Springer
Multigenerational evaluation was made in rats on exposure to high fluoride (100 and 200
ppm) to assess neurotoxic potential of fluoride in discrete areas of the brain in terms of lipid …