Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells

CD Anuradha, S Kanno, S Hirano - Free Radical Biology and Medicine, 2001 - Elsevier
It has been suggested that oxidative stress plays a major role in various forms of cell death,
including necrosis and apoptosis. We have previously reported that fluoride (NaF) induces …

Protective effect of resveratrol on fluoride induced alteration in protein and nucleic acid metabolism, DNA damage and biogenic amines in rat brain

S Pal, C Sarkar - Environmental toxicology and pharmacology, 2014 - Elsevier
Fluoride, a well-established environmental carcinogen, has been found to cause various
neurodegenerative diseases in human. Sub-acute exposure to fluoride at a dose of 20 …

Fluoride-induced hepatotoxicity is prevented by L-Arginine supplementation via suppression of oxidative stress and stimulation of nitric oxide production in rats

AS Akinrinde, M Tijani, OA Awodele… - Toxicology and …, 2021 - Springer
Objective Concerns over fluoride toxicity have increased in recent times due to high
exposures from various anthropogenic sources such as industrial sites, fluoride-containing …

Influence of methionine on toxicity of fluoride in the liver of rats

I Błaszczyk, E Birkner, S Kasperczyk - Biological trace element research, 2011 - Springer
Oxidative stress is a common mechanism by which chemical toxicity can occur in the liver.
The aim of the studies conducted has been to determine what influence the administration of …

Effects of fluoride exposure on mitochondrial function: energy metabolism, dynamics, biogenesis and mitophagy

SH Avila-Rojas, OE Aparicio-Trejo… - Environmental …, 2022 - Elsevier
Fluoride is ubiquitous in the environment. Furthermore, drinking water represents the main
source of exposure to fluoride for humans. Interestingly, low fluoride concentrations have …

[PDF][PDF] Differential in vivo genotoxic effects of lower and higher concentrations of fluoride in mouse bone marrow cells

S Podder, A Chattopadhyay, S Bhattacharya, MR Ray - Fluoride, 2008 - researchgate.net
In an in vivo genotoxicity investigation of the action of fluoride (F) on bone marrow cells,
sodium fluoride (NaF) was administered through the drinking water of 2–3 month old Swiss …

The effects of vitamin D application on NaF-induced cytotoxicity in osteoblast cells (hFOB 1.19)

S Dede, M Taşpinar, V Yüksek, S Çetin… - Biological Trace Element …, 2023 - Springer
This study was planned to evaluate the effect of vitamin D administration on cytotoxicity due
to fluoride exposure in vitro. NaF (IC50) and vitamin D (proliferative) were applied to human …

Fluoride-induced histopathology and synthesis of stress protein in liver and kidney of mice

A Chattopadhyay, S Podder, S Agarwal… - Archives of …, 2011 - Springer
Selective low (15 mg sodium fluoride (NaF)/L) and relatively high (150 mg NaF/L) doses of
in vivo fluoride (F) treatment to Swiss albino mice through drinking water elicited organ …

Rescuing fluoride-induced damages in liver with gamma aminobutyric acid

H Yang, R Xing, S Liu, H Yu, P Li - Biochemical and Biophysical Research …, 2017 - Elsevier
Fluorine poisoning affects human health all over the world and an urgent task is to develop
alleviative medicine to recover or ameliorate the damages to the body. Here we studied the …

Distribution of fluoride in plasma, brain, and bones and associated oxidative damage after induced chronic fluorosis in Wistar rats

P Sharma, PK Verma, S Sood, R Singh, A Gupta… - Biological trace element …, 2022 - Springer
The study was aimed to determine fluoride levels in plasma, brain, and bones of Wistar rats
following chronic administration of fluoride at different dose levels and the consequent …