[HTML][HTML] Molecular surveillance of Plasmodium falciparum drug resistance markers in clinical samples from Botswana

L Tawe, M Menegon, P Ramatlho… - The American Journal …, 2018 - ncbi.nlm.nih.gov
Drug-resistant Plasmodium falciparum is a major threat to global malaria control and
elimination efforts. In Botswana, a southern African country approaching malaria elimination …

Detection of Artemisinin Resistance Marker Kelch-13 469Y in Plasmodium falciparum, South Kivu, Democratic Republic of the Congo, 2022.

W van Loon, BC Bisimwa, V Byela, R Kirby… - The American Journal …, 2024 - europepmc.org
Partial artemisinin resistance has emerged in East Africa, posing a threat to malaria control
across the continent. The Democratic Republic of the Congo carries one of the heaviest …

Trends of Plasmodium falciparum molecular markers associated with resistance to artemisinins and reduced susceptibility to lumefantrine in Mainland Tanzania from …

C Bakari, CI Mandara, RA Madebe, MD Seth… - Malaria Journal, 2024 - Springer
Abstract Background Therapeutic efficacy studies (TESs) and detection of molecular
markers of drug resistance are recommended by the World Health Organization (WHO) to …

Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria

M Tola, O Ajibola, ET Idowu, O Omidiji, ST Awolola… - BMC research …, 2020 - Springer
Objective Nigeria bears 25% of global malaria burden despite concerted efforts towards its
control and elimination. The emergence of drug resistance to first line drugs, artemisinin …

Prevalence of mutations in Plasmodium falciparum genes associated with resistance to different antimalarial drugs in Nyando, Kisumu County in Kenya

KB Musyoka, JN Kiiru, E Aluvaala, P Omondi… - Infection, Genetics and …, 2020 - Elsevier
Resistance to the mainstay antimalarial drugs is a major concern in the control of malaria.
Delayed Plasmodium falciparum parasite clearance has been associated with Single …

Increase of Plasmodium falciparum parasites carrying lumefantrine-tolerance molecular markers and lack of South East Asian pfk13 artemisinin-resistance mutations …

A Konaté-Touré, AP Gnagne, AV Bedia-Tanoh… - Journal of Parasitic …, 2024 - Springer
One of the major obstacles to malaria elimination in the world is the resistance in
Plasmodium falciparum to most antimalarial drugs. This study aimed to estimate the …

Molecular profile of malaria drug resistance markers of Plasmodium falciparum in Suriname

SM Chenet, SA Okoth, J Kelley, N Lucchi… - Antimicrobial agents …, 2017 - Am Soc Microbiol
In Suriname, an artesunate monotherapy therapeutic efficacy trial was recently conducted to
evaluate partial artemisinin resistance emerging in Plasmodium falciparum. We genotyped …

Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance

J Marfurt, TA Smith, IM Hastings, I Müller, A Sie, O Oa… - Malaria journal, 2010 - Springer
Background Molecular monitoring of parasite resistance has become an important
complementary tool in establishing rational anti-malarial drug policies. Community surveys …

Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based …

J Raman, FM Kagoro, A Mabuza, G Malatje, A Reid… - Malaria journal, 2019 - Springer
Abstract Background The ability of Plasmodium falciparum parasites to develop resistance
to widely used anti-malarials threatens malaria control and elimination efforts. Regular drug …

Increased pfmdr1 Copy Number and Sequence Polymorphisms in Plasmodium falciparum Isolates from Sudanese Malaria Patients Treated with Artemether …

NB Gadalla, I Adam, SE Elzaki, S Bashir… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Molecular markers for surveillance of Plasmodium falciparum resistance to current
antimalarials are sorely needed. A 28-day efficacy study of artemether-lumefantrine in …