Skeletal stem cells—a paradigm shift in the field of craniofacial bone tissue engineering

R Tevlin, MT Longaker, DC Wan - Frontiers in dental medicine, 2020 - frontiersin.org
Defects of the craniofacial skeleton arise as a direct result of trauma, diseases, oncological
resection, or congenital anomalies. Current treatment options are limited, highlighting the …

Stem cells regenerating the craniofacial skeleton: current state-of-the-art and future directions

JD Oliver, W Madhoun, EM Graham… - Journal of Clinical …, 2020 - mdpi.com
The craniofacial region comprises the most complex and intricate anatomical structures in
the human body. As a result of developmental defects, traumatic injury, or neoplastic tissue …

Challenges of stem-cell-based craniofacial regeneration

R Xu, C Zhou, Y Zhang, S Zhang… - Current Stem Cell …, 2021 - ingentaconnect.com
Oral diseases, such as dental caries, pulpitis, periodontitis, and craniofacial trauma, are
common. Some individuals suffer from oral cancer or congenital craniofacial defects. The …

The role of skeletal stem cells in the reconstruction of bone defects

MP Murphy, D Irizarry, M Lopez, AL Moore… - Journal of …, 2017 - journals.lww.com
Craniofacial surgery, since its inauguration, has been the culmination of collaborative efforts
to solve complex congenital, dysplastic, oncological, and traumatic cranial bone defects …

Stem cell–based bioengineering of craniofacial bone

DD Lo, DT Montoro, M Grova, JS Hyun… - Stem Cells in …, 2013 - Wiley Online Library
The osteoprogenitor cells represent the cornerstone of novel craniofacial bone engineering,
this chapter emphasizes that these cells alone are inadequate to achieve bone tissue …

Spatial distributions, characteristics, and applications of craniofacial stem cells

G Zhang, Q Li, Q Yuan, S Zhang - Stem Cells International, 2020 - Wiley Online Library
Stem cells play an irreplaceable role in the development, homeostasis, and regeneration of
the craniofacial bone. Multiple populations of tissue‐resident craniofacial skeletal stem cells …

The use of adult stem cells in rebuilding the human face

PG Robey, P Bianco - The Journal of the American Dental Association, 2006 - Elsevier
Background Stem cells have been isolated from a variety of embryonic and postnatal (adult)
tissues, including bone marrow. Bone marrow stromal cells (BMSCs), which are non–blood …

Dental and skeletal stem cells: potential cellular therapeutics for craniofacial regeneration

PH Krebsbach, PG Robey - Journal of dental education, 2002 - Wiley Online Library
The study of stem cells has received considerable attention since the discovery that adult
stem cells have the capacity to form many different tissue types. Technical advances have …

Clinical applications of stem cells in craniofacial surgery

CM Runyan, JA Taylor - Facial plastic surgery, 2010 - thieme-connect.com
Few areas of translational medicine carry as much excitement and hope as stem cell
therapies. Because of recent advances in material science and stem cell and developmental …

Skeletal tissue engineering using mesenchymal or embryonic stem cells: clinical and experimental data

Z Gamie, RJ MacFarlane, A Tomkinson… - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: Mesenchymal stem cells (MSCs) can be obtained from a wide variety of tissues
for bone tissue engineering such as bone marrow, adipose, birth-associated, peripheral …