Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans

C Coelho, ACO Souza, LS Derengowski… - The Journal of …, 2015 - journals.aai.org
Human infection with Cryptococcus neoformans, a common fungal pathogen, follows
deposition of yeast spores in the lung alveoli. The subsequent host–pathogen interaction …

Immunization with a heat-killed prm1 deletion strain protects the host from Cryptococcus neoformans infection

C Li, Y Meng, H Li, W Du, X Gao, C Suo… - Emerging Microbes & …, 2023 - Taylor & Francis
Systemic infection with Cryptococcus neoformans, a dangerous and contagious pathogen
found throughout the world, frequently results in lethal cryptococcal pneumonia and …

Innate Immune Responses to Cryptococcus

LJ Heung - Journal of fungi, 2017 - mdpi.com
Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

Cryptococcus neoformans Gene Expression during Experimental Cryptococcal Meningitis

BR Steen, S Zuyderduyn, DL Toffaletti, M Marra… - Eukaryotic …, 2003 - Am Soc Microbiol
Cryptococcus neoformans, an encapsulated basidiomycete fungus of medical importance, is
capable of crossing the blood-brain barrier and causing meningitis in both …

Mechanisms of cryptococcal virulence and persistence

MA Olszewski, Y Zhang, GB Huffnagle - Future microbiology, 2010 - Taylor & Francis
Cryptococcus neoformans is an environmental yeast that is a leading cause of fatal mycosis
in AIDS patients and a major cause of meningoencephalitis and CNS-related mortality …

Identification of Cryptococcus neoformans Temperature-Regulated Genes with a Genomic-DNA Microarray

PR Kraus, MJ Boily, SS Giles, JE Stajich, A Allen… - Eukaryotic …, 2004 - Am Soc Microbiol
The ability to survive and proliferate at 37° C is an essential virulence attribute of pathogenic
microorganisms. A partial-genome microarray was used to profile gene expression in the …

Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans

DH Yang, KW Jung, S Bang, JW Lee, MH Song… - Genetics, 2017 - academic.oup.com
Thermotolerance is a crucial virulence attribute for human pathogens, including the fungus
Cryptococcus neoformans that causes fatal meningitis in humans. Loss of the protein kinase …

Identification and Characterization of an SKN7 Homologue in Cryptococcus neoformans

FL Wormley Jr, G Heinrich, JL Miller… - Infection and …, 2005 - Am Soc Microbiol
Cryptococcus neoformans is an encapsulated fungal pathogen that primarily infects the
central nervous system of immunocompromised individuals, causing life-threatening …

The ER stress response and host temperature adaptation in the human fungal pathogen Cryptococcus neoformans

VE Glazier, JC Panepinto - Virulence, 2014 - Taylor & Francis
In all eukaryotic cells, the ER stress response is pivotal to survival and adaptation under
stress conditions. During temperature adaptation in the human fungal pathogen …

Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host

TR O'Meara, C Hay, MS Price, S Giles… - Eukaryotic cell, 2010 - Am Soc Microbiol
Cryptococcus neoformans is an environmental fungus and an opportunistic human
pathogen. Previous studies have demonstrated major alterations in its transcriptional profile …