In a breast tumor xenograft model, the MCT-1 oncogene increases the in vivo tumorgenicity
of MCF7 cells by promoting angiogenesis and inhibiting apoptosis. Increases in the tumor …

AU-rich elements (AREs) control the expression of numerous genes by accelerating the
decay of their mRNAs. Rapid decay and deadenylation of β-globin mRNA containing AU …

Global mRNA abundance depends on the balance of synthesis and decay of a population of
mRNAs. To account for this balance during activation of T cells, we used metabolic labeling …

An important paradigm for post‐transcriptional regulation is the control of cytoplasmic mRNA
stability mediated by AU‐rich elements (AREs) in the 3′ untranslated region of transcripts …

Post-transcriptional regulation of gene expression involves multiple checkpoints at which
decisions are made concerning the fate of each messenger RNA species. Primary …

AU-rich elements (AREs) located in the 3′ untranslated region target the mRNAs encoding
many protooncoproteins, cytokines, and lymphokines for rapid degradation. HuR, a …

The control of eukaryotic gene expression occurs at multiple levels, from transcription to
messenger RNA processing, transport, localization, turnover, and translation. RNA-binding …

Altered expression of RNA-binding proteins modulates gene expression in association with
mRNAs encoding many proto-oncogenes, cytokines, chemokines, and proinflammatory …

RNA-binding proteins (RBPs) are key regulators of posttranscriptional gene expression and
control many important biological processes including cell proliferation, development, and …

The importance of precise co-and post-transcriptional processing of RNA in the regulation of
gene expression has become increasingly clear. RNA-binding proteins (RBPs) are a class …