LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR
The function of the vast majority of mammalian long noncoding (lnc) RNAs remains
unknown. Here, analysis of a highly abundant mammalian lncRNA, OIP5-AS1, known as …
unknown. Here, analysis of a highly abundant mammalian lncRNA, OIP5-AS1, known as …
Diverse molecular functions of Hu proteins
MN Hinman, H Lou - Cellular and molecular life sciences, 2008 - Springer
Hu proteins are RNA-binding proteins involved in diverse biological processes. The
neuronal members of the Hu family, HuB, HuC, and HuD play important roles in neuronal …
neuronal members of the Hu family, HuB, HuC, and HuD play important roles in neuronal …
Expression of the RNA-binding protein HuR and its clinical significance in human stage I and II lung adenocarcinoma
The ubiquitously expressed RNA-binding protein Hu antigen (HuR) participates in the post-
transcriptional regulation of mRNAs bearing U-and AU-rich sequences. Expression of HuR …
transcriptional regulation of mRNAs bearing U-and AU-rich sequences. Expression of HuR …
Androgens regulate the binding of endogenous HuR to the AU-rich 3′ UTRs of HIF-1α and EGF mRNA
LG Sheflin, AP Zou, SW Spaulding - Biochemical and biophysical research …, 2004 - Elsevier
The 3′ UTRs of mammalian HIF-1α and EGF mRNA contain several highly conserved AU-
rich elements (ARE) known to control the turnover of labile mRNAs by binding ARE-binding …
rich elements (ARE) known to control the turnover of labile mRNAs by binding ARE-binding …
[HTML][HTML] Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis
J Wang, Y Guo, H Chu, Y Guan, J Bi… - International journal of …, 2013 - mdpi.com
The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …
The RNA-binding protein HuR in human cancer: A friend or foe?
The RNA-binding proteins (RBPs) are critical trans factors that associate with specific cis
elements present in mRNAs whose stability and translation are subject to regulation. The …
elements present in mRNAs whose stability and translation are subject to regulation. The …
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
A Lal, K Mazan‐Mamczarz, T Kawai, X Yang… - The EMBO …, 2004 - embopress.org
RNA‐binding proteins HuR and AUF1 bind to many common AU‐rich target mRNAs and
exert opposing influence on target mRNA stability, but the functional interactions between …
exert opposing influence on target mRNA stability, but the functional interactions between …
[HTML][HTML] Intracellular localization and interaction of mRNA binding proteins as detected by FRET
PS David Gerecht, MA Taylor, JD Port - BMC cell biology, 2010 - Springer
Background A number of RNA binding proteins (BPs) bind to A+ U rich elements (AREs),
commonly present within 3'UTRs of highly regulated RNAs. Individual RNA-BPs proteins …
commonly present within 3'UTRs of highly regulated RNAs. Individual RNA-BPs proteins …
[HTML][HTML] Low Molecular Weight Inhibitors Targeting the RNA-Binding Protein HuR
BP Joseph, V Weber, L Knüpfer, A Giorgetti… - International Journal of …, 2023 - mdpi.com
The RNA-binding protein human antigen R (HuR) regulates stability, translation, and
nucleus-to-cytoplasm shuttling of its target mRNAs. This protein has been progressively …
nucleus-to-cytoplasm shuttling of its target mRNAs. This protein has been progressively …