[HTML][HTML] Insights into the evolving roles of circular RNAs in cancer

KL Harper, TJ Mottram, A Whitehouse - Cancers, 2021 - mdpi.com
Simple Summary The central dogma of RNA biology was traditionally governed by the
transcription of DNA into messenger RNA (mRNA) followed by translation into protein. As …

[HTML][HTML] Circular RNAs in cancer: opportunities and challenges in the field

LS Kristensen, TB Hansen, MT Venø, J Kjems - Oncogene, 2018 - nature.com
Circular RNA (circRNA) is a novel member of the noncoding cancer genome with distinct
properties and diverse cellular functions, which is being explored at a steadily increasing …

[HTML][HTML] Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …

[HTML][HTML] Circular RNAs in Cancer: emerging functions in hallmarks, stemness, resistance and roles as potential biomarkers

M Su, Y Xiao, J Ma, Y Tang, B Tian, Y Zhang, X Li… - Molecular cancer, 2019 - Springer
Circular RNAs (circRNAs) are a class of RNA molecules with closed loops and high stability.
CircRNAs are abundantly expressed in eukaryotic organisms and exhibit both location-and …

[HTML][HTML] Circular RNAs: emerging role in cancer diagnostics and therapeutics

A Rajappa, S Banerjee, V Sharma… - Frontiers in molecular …, 2020 - frontiersin.org
Circular RNAs (circRNAs) are rapidly coming to the fore as major regulators of gene
expression and cellular functions. They elicit their influence via a plethora of diverse …

Circular RNAs: insights into clinical and therapeutic approaches for various cancers

F Akram, N Nasir, FI Shah - Current Protein and Peptide …, 2023 - ingentaconnect.com
Background: With the advent of cancer diagnostics and therapeutics, circular RNAs
(circRNAs) are swiftly becoming one of the significant regulators of gene expression and …

Circular RNAs and cancer: Opportunities and challenges

C Sole, CH Lawrie - Advances in Clinical Chemistry, 2020 - Elsevier
Circular RNAs (circRNAs) are covalently circularized RNA moieties that despite being
relatively abundant were only recently identified and have only begun to be investigated …

[HTML][HTML] Circular RNAs in the tumour microenvironment

Z Ma, Y Shuai, X Gao, X Wen, J Ji - Molecular Cancer, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) are a new class of endogenous non-coding
RNAs (ncRNAs) widely expressed in eukaryotic cells. Mounting evidence has highlighted …

[HTML][HTML] New molecular mechanisms and clinical impact of circRNAs in human cancer

G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …

[HTML][HTML] Circular RNAs: emerging cancer biomarkers and targets

Y Zhang, W Liang, P Zhang, J Chen, H Qian… - Journal of Experimental …, 2017 - Springer
CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are
abundant in eukaryotic transcripts and show certain levels of tissue and cell specificity …