FRET-based cGMP Imaging in the Nervous System
S Peters - 2024 - tobias-lib.ub.uni-tuebingen.de
Impaired cyclic 3'5'guanosine monophosphate (cGMP) signaling has been linked to several
neurological disorders, including inaccurate axon formation and pathfinding. It is well known …
neurological disorders, including inaccurate axon formation and pathfinding. It is well known …
[HTML][HTML] cGMP imaging in brain slices reveals brain region-specific activity of NO-sensitive guanylyl cyclases (NO-GCs) and NO-GC stimulators
S Peters, M Paolillo, E Mergia, D Koesling… - International journal of …, 2018 - mdpi.com
Impaired NO-cGMP signaling has been linked to several neurological disorders. NO-
sensitive guanylyl cyclase (NO-GC), of which two isoforms—NO-GC1 and NO-GC2—are …
sensitive guanylyl cyclase (NO-GC), of which two isoforms—NO-GC1 and NO-GC2—are …
Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3
H Schmidt, S Peters, K Frank, L Wen… - European Journal of …, 2016 - Wiley Online Library
A cyclic GMP (cGMP) signaling pathway, comprising C‐type natriuretic peptide (CNP), its
guanylate cyclase receptor Npr2, and cGMP‐dependent protein kinase I, is critical for the …
guanylate cyclase receptor Npr2, and cGMP‐dependent protein kinase I, is critical for the …
Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice
In hippocampus, two guanylyl cyclases (NO-GC1 and NO-GC2) are involved in the
transduction of the effects of nitric oxide (NO) on synaptic transmission. However, the …
transduction of the effects of nitric oxide (NO) on synaptic transmission. However, the …
[HTML][HTML] Real-Time Imaging Reveals Augmentation of Glutamate-Induced Ca2+ Transients by the NO-cGMP Pathway in Cerebellar Granule Neurons
M Paolillo, S Peters, A Schramm… - International journal of …, 2018 - mdpi.com
Dysfunctions of NO-cGMP signaling have been implicated in various neurological disorders.
We have studied the potential crosstalk of cGMP and Ca2+ signaling in cerebellar granule …
We have studied the potential crosstalk of cGMP and Ca2+ signaling in cerebellar granule …
NO/cGMP: the past, the present, and the future
M Russwurm, C Russwurm, D Koesling… - Guanylate Cyclase and …, 2013 - Springer
The NO/cGMP signalling cascade participates in the regulation of physiological parameters
such as smooth muscle relaxation, inhibition of platelet aggregation, and neuronal …
such as smooth muscle relaxation, inhibition of platelet aggregation, and neuronal …
Hippocampal AMPA‐and NMDA‐induced cGMP signals are mainly generated by NO‐GC2 and are under tight control by PDEs 1 and 2
J Giesen, E Mergia, D Koesling… - European Journal of …, 2022 - Wiley Online Library
In the central nervous system, the nitric oxide (NO)/cyclic guanosine monophosphate
(cGMP) signalling cascade has an established role in fine‐tuning of synaptic transmission …
(cGMP) signalling cascade has an established role in fine‐tuning of synaptic transmission …
Robust and sensitive GFP-based cGMP sensor for real time imaging in intact Caenorhabditis elegans
S Woldemariam, J Nagpal, J Li, MW Schneider… - bioRxiv, 2018 - biorxiv.org
Abstract cGMP is a ubiquitous second messenger that plays a role in sensory signaling and
plasticity through its regulation of ion channels and kinases. Previous studies that primarily …
plasticity through its regulation of ion channels and kinases. Previous studies that primarily …
[HTML][HTML] The NO/cGMP pathway inhibits transient cAMP signals through the activation of PDE2 in striatal neurons
M Polito, J Klarenbeek, K Jalink… - Frontiers in cellular …, 2013 - frontiersin.org
The NO-cGMP signaling plays an important role in the regulation of striatal function although
the mechanisms of action of cGMP specifically in medium spiny neurons (MSNs) remain …
the mechanisms of action of cGMP specifically in medium spiny neurons (MSNs) remain …
[HTML][HTML] Simultaneous detection of both GDNF and GFRα1 expression patterns in the mouse central nervous system
C Ortega-de San Luis, A Pascual - Frontiers in neuroanatomy, 2016 - frontiersin.org
Glial cell line-derived neurotrophic factor (GDNF) is proposed as a therapeutic tool in
Parkinson's disease, addiction-related disorders, and neurodegenerative conditions …
Parkinson's disease, addiction-related disorders, and neurodegenerative conditions …