Abstract β-Carbolines are indole alkaloids having a tricyclic pyrido [3, 4-b] indole ring in their
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …

Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

Cancer, an uncontrolled and rapid proliferation of abnormal cells, has become one of the
leading cause of death worldwide. The development of resistance among the numerous …

Cell cycle dysregulation is the mainstay of aberrant cell proliferation, which leads to tumor
progression. Mutations in tumor cells initiate various dysregulated pathways and …

β-Carboline alkaloids are a large group of natural and synthetic indole alkaloids with
different degrees of aromaticity, some of which are widely distributed in nature, including …

A series of 1-indolyl substituted β-carbolines including the natural products
hyrtiosulawesine, pityriacitrin and pityriacitrin B were prepared via Pictet–Spengler …

To further our SAR study on the chemistry and antitumor activity/neurotoxicity of β-carboline
alkaloids, several series of β-carboline derivatives with various substituents were designed …

Abstract γ-Carboline alkaloids are a family of natural and synthetic agents that have diverse
bioactivities including antiviral, antibacterial, antifungal, antiparasitic, antitumor, anti …

A series of 1-substituted 1, 2, 3, 4-tetrahydro-and 3, 4-dihydro-b-carboline derivatives have
been synthesized and evaluated for antitumor activity against murine P-388 and human …

Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …