Translocations involving chromosome 11q23 frequently occur in pediatric acute myeloid
leukemia (AML) and are associated with poor prognosis. In most cases, the MLL gene is …

Background: In the past three decades, there has been significant improvements in the
diagnosis and management of acute myeloid leukaemia. Cytogenetic and molecular genetic …

This retrospective study aimed to analyze the treatment effect and prognostic factors of
pediatric acute myeloid leukemia (AML) patients with t (8; 21). A total of 268 newly …

A novel association of t (11; 19)(q23; p13) and t (5; 16)(q13; q22) was detected by G-
banding and spectral karyotyping studies in an 18-year-old patient. While balanced t (11; …

The t (7; 12)(q36; p13) is one of the recurrent cytogenetic abnormalities that involves the
ETV6 gene. It is found in patients suffering with infantile acute myeloid leukemia (AML). We …

Background Individuals with congenital Trisomy 21 (+ 21) have an increased risk of
developing acute myeloid leukemia (AML). AML with+ 21 has traditionally been regarded as …

Patients with infant acute myeloid leukemia (AML) who carry at (7; 12)(q36; p13)
translocation have been reported to have a poor clinical outcome. MNX1–ETV6 fusion …

NUP98 rearrangements are recurrent genetic events in pediatric acute myeloid leukemia
(AML). We identified NPU98-NSD1 as a recurrent poor risk abnormality (Hollink et al, Blood …

Abstract The cryptic translocation t (5; 11)(q35; p15. 5), which creates a NSD1‐NUP98
fusion gene, has been associated with a deletion of the long arm of chromosome 5, del (5q) …

Acute myeloid leukaemia carrying the translocation t (7; 12)(q36; p13) is an adverse-risk
leukaemia uniquely observed in infants. Despite constituting up to 30% of cases in under 2 …