Aim. To study characteristics of 11q23 involvement, age-specific differences in the incidence
of these chromosomal markers in acute myeloid leukemias (AML) in children, and to …

To study the prognostic relevance of rare genetic aberrations in acute myeloid leukemia
(AML), such as t (16; 21), international collaboration is required. Two different types of t (16; …

Partial deletion of the long arm of chromosome 5, del (5q), is the cytogenetic hallmark of the
5q-syndrome, a distinct subtype of myelodysplastic syndrome-refractory anemia (MDS-RA) …

Background Alterations of 11q23/KMT2A are the most prevalent cytogenetic abnormalities in
acute myeloid leukemia (AML) and the prognostic significance of 11q23/KMT2A‐rearranged …

The cytogenetically cryptic t (5; 11)(q35; p15) leading to the NUP98‐NSD1 fusion is a rare
but recurrent gene rearrangement recently reported to identify a group of young AML …

Background Acute myeloid leukemia (AML) with myelodysplasia-related changes is
currently defined on the basis of morphologic features of myelodysplasia in at least 50% of …

A reciprocal translocation (9; 11) is often found in acute myeloid leukemia (AML), mostly of
the M5a type. We report a case of a child with AML, in whom t (9; 11) was observed at …

Introduction: Non-random cytogenetic aberrations are often involved in the development of
AML in children and several aberrations can serve as diagnostic markers, prognosis …

BACKGROUND Chromosome i (17)(q10) abnormality is mainly associated with chronic
myeloid leukemia (CML), myelodysplastic syndrome/myeloproliferative tumors (MDS/MPD) …

Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of
AML. The uncommon MLL-SEPT6 rearrangement results from t (X; 11) or other variants like …