The massive scale of the global SARS-CoV-2 sequencing effort created new opportunities
and challenges for understanding SARS-CoV-2 evolution. Rapid detection and assessment …

Effective systems for the analysis of molecular data are fundamental for monitoring the
spread of infectious diseases and studying pathogen evolution. The rapid identification of …

Analysis of SARS-CoV-2 genetic diversity within infected hosts can provide insight into the
generation and spread of new viral variants and may enable high resolution inference of …

Repeated emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with increased fitness underscores the value of rapid detection and characterization …

Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

Genetic diversity of SARS-CoV-2 (formerly 2019-nCoV), the virus which causes COVID-19,
provides information about epidemic origins and the rate of epidemic growth. By analysing …

COVID-19 is caused by the coronavirus SARS-CoV-2, which jumped into the human
population in late 2019 from a currently uncharacterised animal reservoir. Due to this recent …

Abstract Background The Centers for Disease Control and Prevention contracted with
laboratories to sequence the SARS-CoV-2 genome from positive samples across the United …

The COVID-19 pandemic has been characterised by sequential variant-specific waves
shaped by viral, individual human and population factors. SARS-CoV-2 variants are defined …

The high transmission and mortality rates associated with SARS-CoV-2 have led to tragic
consequences worldwide. Large-scale whole-genome sequencing of the SARS-CoV-2 …