(1) Background: Acute ischemic stroke (IS) is one of the main causes of human disability and
death. Therefore, multifunctional nanosystems that effectively cross the blood–brain barrier …

Designing translational antioxidative agents that could scavenge free radicals produced
during reperfusion in brain ischemia stroke and alleviate neurologic damage is the main …

Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …

Background Ischemic stroke is one of the most serious global public health problems.
However, the performance of current therapeutic regimens is limited due to their poor target …

Following stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates
neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients …

Ischemic stroke is caused by cerebrovascular stenosis or occlusion. Excessive reactive
oxygen species (ROS) are the focus‐triggering factor of irreversible injury in ischemic …

Acute ischemic stroke has become the major cause of mortality and disability worldwide.
Following ischemic stroke, the reperfusion injury is mainly mediated by the burst of reactive …

Oxidative stress and a series of excessive inflammatory responses are major obstacles for
neurological functional recovery after ischemic stroke. Effective noninvasive anti …

Reperfusion injury is still a major challenge that impedes neuronal survival in ischemic
stroke. However, the current clinical treatments are remained on single pathological …

Nanozymes, which can selectively scavenge reactive oxygen species (ROS), have recently
emerged as promising candidates for treating ischemic stroke and traumatic brain injury …