Factors affecting the pharmacokinetics and pharmacodynamics of liposomal drugs

G Song, H Wu, K Yoshino… - Journal of liposome …, 2012 - Taylor & Francis
Various attempts to increase the therapeutic index of the drug while minimizing side effects
have been made in drug delivery systems. Among several promising strategies, liposomes …

Drug delivery systems. 1. Site‐specific drug delivery using liposomes as carriers

VV Ranade - The Journal of Clinical Pharmacology, 1989 - Wiley Online Library
Drug delivery systems, offering controlled delivery of biologically active agents, are rapidly
gaining importance in pharmaceutical research and development. To achieve controlled …

Liposomal drug formulations: rationale for development and what we can expect for the future

TM Allen - Drugs, 1998 - Springer
Liposomes are versatile drug carriers which can be used to solve problems of drug
solubility, instability and rapid degradation. Both hydrophilic and hydrophobic drugs can be …

Drug delivery strategies for poorly water-soluble drugs: the industrial perspective

P van Hoogevest, X Liu, A Fahr - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: For poorly soluble compounds, a good bioavailability is typically needed to
assess the therapeutic index and the suitability of the compound for technical development …

A review on composite liposomal technologies for specialized drug delivery

MS Mufamadi, V Pillay, YE Choonara… - Journal of drug …, 2011 - Wiley Online Library
The combination of liposomes with polymeric scaffolds could revolutionize the current state
of drug delivery technology. Although liposomes have been extensively studied as a …

A review of liposomes as a drug delivery system: current status of approved products, regulatory environments, and future perspectives

P Liu, G Chen, J Zhang - Molecules, 2022 - mdpi.com
Liposomes have been considered promising and versatile drug vesicles. Compared with
traditional drug delivery systems, liposomes exhibit better properties, including site …

Small molecule therapeutic-loaded liposomes as therapeutic carriers: from development to clinical applications

JY Hwang, Z Li, XJ Loh - RSC advances, 2016 - pubs.rsc.org
While small hydrophilic therapeutic molecules have proved to be exceptionally effective in
curing diseases, their in vivo efficacy remains low. Small molecule therapeutics infused in …

Pharmacokinetics of long-circulating liposomes

TM Allen, CB Hansen, DEL de Menezes - Advanced Drug Delivery …, 1995 - Elsevier
Association of drugs with carriers such as liposomes has marked effects on both the
pharmacokinetic profiles of the carrier and of the carrier-associated drug. In general …

Tumor targeting using liposomal antineoplastic drugs

J Huwyler, J Drewe, S Krähenbühl - International journal of …, 2008 - Taylor & Francis
During the last years, liposomes (microparticulate phospholipid vesicles) have been used
with growing success as pharmaceutical carriers for antineoplastic drugs. Fields of …

[PDF][PDF] An Updated Review on: Liposomes as drug delivery system

D Sharma, AAE Ali, LR Trivedi - PharmaTutor, 2018 - researchgate.net
Liposomes are most placed acquiring in pharma industries and very useful in the various
drug delivery system used to target the drug to particular tissue. Because of structural …