Clinical significance of estrogen receptor β in breast cancer

S Saji, M Hirose, M Toi - Cancer chemotherapy and pharmacology, 2005 - Springer
Ever since the estrogen receptor (ER) β was discovered in 1996, we have been trying to
determine its value as a prognostic and/or predictive factor in breast cancer and its potential …

Clinical impact of assay of estrogen receptor βcx in breast cancer

S Saji, Y Omoto, C Shinizu, S Horiguchi, T Watanabe… - Breast Cancer, 2002 - Springer
Since 1996 when estrogen receptor β (ERβ) was discovered, much effort has been devoted
to the question of the value of ERβ as a prognostic and/or predictive factor in breast cancer …

Estrogen receptor beta in breast cancer—diagnostic and therapeutic implications

J Hartman, A Ström, JÅ Gustafsson - Steroids, 2009 - Elsevier
More than 10 years have passed since the discovery of the second estrogen receptor,
estrogen receptor β (ERβ). It is now evident that ERα is not the only ER in breast cancer …

Oestrogen receptor β in breast cancer: good, bad or still too early to tell?

V Speirs - The Journal of Pathology: A Journal of the …, 2002 - Wiley Online Library
Two oestrogen receptors (ERs), ERα and ERβ, have been identified. ERα is by far the better
characterized and is an established predictive marker in breast cancer which influences …

Estrogen receptor β in breast cancer: associations between ERβ, hormonal receptors, and other prognostic biomarkers

Y Choi, M Pinto - Applied Immunohistochemistry & Molecular …, 2005 - journals.lww.com
The estrogen receptor (ER)-β isoform has been recently identified to be distinct from ERα
isoform and regulates separate sets of genes, and can exert opposite signaling functions …

Clinical significance of the expression of estrogen receptors α and β for endocrine therapy of breast cancer

H Iwase, Z Zhang, Y Omoto, H Sugiura… - Cancer chemotherapy …, 2003 - Springer
The assessment of the estrogen receptor (ER) α and the progesterone receptor (PgR) in
breast cancer tissues is important for discriminating between hormone-dependent and …

Estrogen receptor β protein in human breast cancer: correlation with clinical tumor parameters

SAW Fuqua, R Schiff, I Parra, JT Moore, SK Mohsin… - Cancer research, 2003 - AACR
The recent discovery of a second estrogen receptor (ER), designated ERβ, raises pressing
questions about its role in estrogen regulation of human breast cancer cells and its …

The role of estrogen receptor-β in breast cancer

LC Murphy, E Leygue - Seminars in reproductive medicine, 2012 - thieme-connect.com
The discovery of a second estrogen receptor (ER), ERβ, has led to a reevaluation of
estrogen action. The widespread expression of ERβ-like proteins in normal and neoplastic …

Coexpression of estrogen receptor α and β: poor prognostic factors in human breast cancer?

V Speirs, AT Parkes, MJ Kerin, DS Walton, PJ Carleton… - Cancer research, 1999 - AACR
The cloning of a second estrogen receptor (ER), ERβ, has prompted a reevaluation of the
role of ERs in breast cancer. The aim of this study was to determine the expression of both …

Estrogen receptors: role in breast cancer

MJ Duffy - Critical reviews in clinical laboratory sciences, 2006 - Taylor & Francis
The estrogen receptor (ER) exists in two forms known as ERα and ERβ. Currently, a clinical
role has only been established for ERα. The primary use of ERα in breast cancer is for …