To estimate the clinical value of estrogen receptor (ER) β expression in breast cancer we
used an immunohistochemical method to detect the wild-type ERβ in 88 primary breast …

Background: Endocrine therapy for breast cancer is now well established and with the
identification of a second oestrogen receptor, ERβ, 3 years ago it is timely to review the …

We addressed the clinicopathological significance of the oestrogen receptor (ER) β protein,
including an ERβ variant, ERβcx, in normal human breast and breast cancer. The reverse …

Estrogen receptor (ER) βcx, a splice variant of ERβ, is a dominant repressor of ERα function.
In this study we investigated the possibility that because the progesterone receptor (PR) …

Breast cancer is one of the most common forms of cancer observed in women. Endogenous
estrogen is thought to play a major role in its development and estrogen receptor blockers …

Purpose: Breast cancer is a hormone-dependent cancer, and the presence of estrogen
receptor α (ER-α) in tumors is used clinically to predict the likelihood of response to …

Despite over 15 years of research, the exact role, if any, played by estrogen receptor β (ERβ)
in human breast cancer remains elusive. A large body of data both in vitro and in vivo …

The recent cloning of a second estrogen receptor (ER), designated ERβ, has prompted a
reevaluation of the role of ERs in breast cancer. We have developed and validated a real …

The overexpression of estrogen receptor alpha (ERalpha) is frequently observed in the early
stage of breast cancer. We previously reported that the specific promoter of the ERalpha …

Two estrogen receptors (ER), ERα and ERβ, are expressed in breast cancer but their role in
treatment response is unclear. The overall objective of this study was to determine if the …