Estrogen receptors and proliferation markers in primary and recurrent breast cancer

EV Jensen, G Cheng, C Palmieri… - Proceedings of the …, 2001 - National Acad Sciences
To elucidate the clinical importance of estrogen receptor (ER) β in breast cancer, 29 archival
primary breast cancer specimens, six locally recurrent cancers, and five benign mammary …

A possible divergent role for the oestrogen receptor alpha and beta subtypes in clinical breast cancer

JM Knowlden, JMW Gee, JFR Robertson… - … journal of cancer, 2000 - Wiley Online Library
We have examined the relative levels of oestrogen receptor beta (ERβ) mRNA in 94 breast
cancer specimens using a semi‐quantitative RT‐PCR procedure. We correlated its …

Estrogen receptor β expression is associated with tamoxifen response in ERα-negative breast carcinoma

SK Gruvberger-Saal, PO Bendahl, LH Saal… - Clinical Cancer …, 2007 - AACR
Purpose: Endocrine therapies, such as tamoxifen, are commonly given to most patients with
estrogen receptor (ERα)–positive breast carcinoma but are not indicated for persons with …

Altered expression pattern of alternatively spliced estrogen receptor β transcripts in breast carcinoma

I Girault, C Andrieu, S Tozlu, F Spyratos, I Bièche… - Cancer letters, 2004 - Elsevier
Dysregulation of total estrogen receptor β (ERβ) expression has been implicated in breast
tumorigenesis. The ERβ gene yields five exon 8 alternatively spliced transcripts (ERβ1–5) …

[HTML][HTML] The potential role of estrogen receptor β2 in breast cancer

JM Baek, BJ Chae, BJ Song, SS Jung - International Journal of Surgery, 2015 - Elsevier
Endocrine therapy is provided to all patients with estrogen receptor (ER)-positive breast
cancer, but only a subset of them derives clinical benefit. The discovery of ERβ and its five …

[HTML][HTML] Is oestrogen receptor-β a predictor of endocrine therapy responsiveness in human breast cancer?

LC Murphy, PH Watson - Endocrine-related cancer, 2006 - erc.bioscientifica.com
The role of oestrogen receptor (ER) β in human breast cancer remains unclear. However, it
is now apparent that when considering ER β in human breast cancer it is important to …

Nuclear and cytoplasmic expression of ERβ1, ERβ2, and ERβ5 identifies distinct prognostic outcome for breast cancer patients

AM Shaaban, AR Green, S Karthik, Y Alizadeh… - Clinical Cancer …, 2008 - AACR
Purpose: Previous conflicting results about the prognostic significance of estrogen receptor
(ER)-β in breast cancer may be explained by contribution of isoforms, of which five exist. Our …

[HTML][HTML] Expression of oestrogen receptor-β in oestrogen receptor-α negative human breast tumours

GP Skliris, E Leygue, L Curtis-Snell, PH Watson… - British journal of …, 2006 - nature.com
To analyse the phenotype of breast tumours that express oestrogen receptor-β (ERβ) alone
tissue microarrays were used to investigate if ERβ isoforms are associated with specific …

Expression and regulation of estrogen receptor beta in human breast tumors and cell lines.

EA Vladusic, AE Hornby… - Oncology …, 2000 - spandidos-publications.com
Expression of estrogen receptor beta (ER-beta) and its regulation by estradiol and anti-
estrogens was analyzed in breast cancer cells. We determined that ER-beta is expressed in …

Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects

Y Omoto, H Iwase - Cancer science, 2015 - Wiley Online Library
Breast and prostate cancers are among the most common of all cancers. They are referred
to as hormone‐dependent cancers, because estrogen and androgen are involved in their …