Interstitial fibrosis is a hallmark structural correlate of progressive and chronic kidney
disease. There remain many uncertainties about how to best measure interstitial fibrosis …

Renal fibrosis is the final common pathway for many kidney lesions that lead to chronic
progressive organ failure. The tubulointerstitial space occupies up to 90% of kidney volume …

Although kidney transplantation has been an important means for the treatment of patients
with end stage of renal disease, the long-term survival rate of the renal allograft remains a …

Elevated expression of the multifunctional cytokine transforming growth factor β1 (TGF-β1) is
causatively linked to kidney fibrosis progression initiated by diabetic, hypertensive …

Matrix metalloproteinase-7 (MMP-7) is a secreted zinc-and calcium-dependent
endopeptidase that degrades a broad range of extracellular matrix substrates and additional …

Background: Proteinuria is a key biomarker in nephrology. It is central to diagnosis and risk
assessment and the primary target of many important therapies. Etiologies resulting in …