Neonatal hypoxia suppresses oligodendrocyte Nogo-A and increases axonal sprouting in a rodent model for human prematurity

J Weiss, B Takizawa, A McGee, WB Stewart… - Experimental …, 2004 - Elsevier
Premature human infants frequently suffer from periventricular leukomalacia (PVL)
characterized by the loss of central myelinated tracts in the brain [Neuropathology, 22 (2002) …

Regulating axon growth within the postnatal central nervous system

F Hu, SM Strittmatter - Seminars in perinatology, 2004 - Elsevier
As neuronal development enters its final stages, axonal growth is restricted. Recent work
indicates that several myelin-derived proteins, Nogo, MAG and OMgp, play a critical role in …

Maturation‐dependent oligodendrocyte apoptosis caused by hyperoxia

B Gerstner, C Bührer, C Rheinländer… - Journal of …, 2006 - Wiley Online Library
In the immature human brain, periventricular leukomalacia (PVL) is the predominant white
matter injury underlying the development of cerebral palsy. PVL has its peak incidence …

Nitric oxide‐induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis‐inducing factor translocation

O Baud, J Li, Y Zhang, RL Neve… - European Journal of …, 2004 - Wiley Online Library
Reactive nitrogen species are thought to be involved in both hypoxic‐ischemic and cytokine‐
induced brain injury, including periventricular leukomalacia (PVL), the major pathological …

Hyperoxia causes maturation-dependent cell death in the developing white matter

B Gerstner, TM DeSilva, K Genz… - Journal of …, 2008 - Soc Neuroscience
Periventricular leukomalacia is the predominant injury in the preterm infant leading to
cerebral palsy. Oxygen exposure may be an additional cause of brain injury in these infants …

Prenatal systemic hypoxia-ischemia and oligodendroglia loss in cerebellum

PC Barradas, T Savignon, AC Manhães… - Glial Cells in Health and …, 2016 - Springer
Hypoxic-ischemic (HI) injury is an important cause of death and disabilities. Despite all
improvements in neonatal care, the number of children who suffer some kind of injury during …

Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury

SA Back, NL Luo, NS Borenstein… - Journal of …, 2001 - Soc Neuroscience
Hypoxic-ischemic injury to the periventricular cerebral white matter [periventricular
leukomalacia (PVL)] results in cerebral palsy and is the leading cause of brain injury in …

Selective vulnerability of late oligodendrocyte progenitors to hypoxia–ischemia

SA Back, BH Han, NL Luo, CA Chricton… - Journal of …, 2002 - Soc Neuroscience
In the premature infant, hypoxic-ischemic damage to the cerebral white matter
[periventricular leukomalacia (PVL)] is a common and leading cause of brain injury that often …

Perinatal hypoxia-ischemia induces apoptotic and excitotoxic death of periventricular white matter oligodendrocyte progenitors

JK Ness, MJ Romanko, RP Rothstein… - Developmental …, 2001 - karger.com
Hypoxia-ischemia (HI) is a leading cause of white matter damage, a major contributor to
cerebral palsy in premature infants. Preferential white matter damage is believed to result …

Mouse intermittent hypoxia mimicking apnoea of prematurity: effects on myelinogenesis and axonal maturation

J Cai, CM Tuong, Y Zhang, CB Shields… - The Journal of …, 2012 - Wiley Online Library
Premature babies are at high risk for both infantile apnoea and long‐term neurobehavioural
deficits. Recent studies suggest that diffuse structural changes in brain white matter are a …