Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression

N Putluri, A Shojaie, VT Vasu, SK Vareed, S Nalluri… - Cancer research, 2011 - AACR
Although alterations in xenobiotic metabolism are considered causal in the development of
bladder cancer, the precise mechanisms involved are poorly understood. In this study, we …

Detection of bladder cancer in human urine by metabolomic profiling using high performance liquid chromatography/mass spectrometry

HJ Issaq, O Nativ, T Waybright, B Luke, TD Veenstra… - The Journal of …, 2008 - Elsevier
PURPOSE: The current use of cystoscopy for screening and detecting bladder cancer is
invasive and expansive. Various urine based biomarkers have been used for this purpose …

Recent advances in the metabolomic study of bladder cancer

CS Amara, V Vantaku, Y Lotan… - Expert review of …, 2019 - Taylor & Francis
Introduction: Metabolomics is a chemical process, involving the characterization of
metabolites and cellular metabolism. Recent studies indicate that numerous metabolic …

Metabolomic approaches for detection and identification of biomarkers and altered pathways in bladder cancer

NA di Meo, D Loizzo, SD Pandolfo, R Autorino… - International Journal of …, 2022 - mdpi.com
Metabolomic analysis has proven to be a useful tool in biomarker discovery and the
molecular classification of cancers. In order to find new biomarkers, and to better understand …

Bladder cancer biomarker discovery using global metabolomic profiling of urine

BM Wittmann, SM Stirdivant, MW Mitchell, JE Wulff… - PloS one, 2014 - journals.plos.org
Bladder cancer (BCa) is a common malignancy worldwide and has a high probability of
recurrence after initial diagnosis and treatment. As a result, recurrent surveillance, primarily …

[HTML][HTML] Diagnosis of bladder cancer and prediction of survival by urinary metabolomics

X Jin, SJ Yun, P Jeong, IY Kim, WJ Kim, S Park - Oncotarget, 2014 - ncbi.nlm.nih.gov
Bladder cancer (BC) is a common cancer but diagnostic modalities, such as cystoscopy and
urinary cytology, have limitations. Here, high-performance liquid chromatography …

Investigation of the urinary metabolic variations and the application in bladder cancer biomarker discovery

X Liu, X Cheng, X Liu, L He, W Zhang… - … journal of cancer, 2018 - Wiley Online Library
Urine metabolomics have been used to identify biomarkers for clinical diseases. However,
inter‐individual variations and effect factors need to be further evaluated. In our study, we …

Integrative metabolomic and transcriptomic analysis for the study of bladder cancer

A Loras, C Suárez-Cabrera, MC Martínez-Bisbal… - Cancers, 2019 - mdpi.com
Metabolism reprogramming is considered a hallmark of cancer. The study of bladder cancer
(BC) metabolism could be the key to developing new strategies for diagnosis and therapy …

Metabolomics analysis reveals distinct profiles of nonmuscle‐invasive and muscle‐invasive bladder cancer

D Sahu, Y Lotan, B Wittmann, B Neri… - Cancer …, 2017 - Wiley Online Library
Urothelial carcinoma is the most common form of bladder cancer, but pathway changes that
occur with stage‐wise progression have not been well defined. We used a metabolomics …

Biomarkers in bladder cancer: A metabolomic approach using in vitro and ex vivo model systems

D Rodrigues, C Jerónimo, R Henrique… - … journal of cancer, 2016 - Wiley Online Library
Metabolomics has recently proved to be useful in the area of biomarker discovery for
cancers in which early diagnostic and prognostic biomarkers are urgently needed, as is the …