Malaria control is hindered by the evolution and spread of resistance to antimalarials,
necessitating multiple changes to drug policies over time. A comprehensive antimalarial …

Molecular surveillance of drug resistance markers through time provides crucial information
on genomic adaptations, especially in parasite populations exposed to changing drug …

Background Over the last two decades, the scale-up of vector control and changes in the first-
line anti-malarial, from chloroquine (CQ) to sulfadoxine-pyrimethamine (SP) and then to …

Background Anti-malarial drug resistance remains a major threat to global malaria control
efforts. In Africa, Plasmodium falciparum remains susceptible to artemisinin-based …

Objectives This study aimed to investigate the evolution of Plasmodium falciparum
antimalarial drug resistance markers by comparing the pre-and post-adoption of artemisinin …

The potential spread of antimalarial drug resistance to Africa, in particular for artemisinins
and key partner drugs, is a major concern. We surveyed Plasmodium falciparum genetic …

Background Although it is well known that drug pressure selects for drug-resistant parasites,
the role of transmission reduction by insecticide-treated bed nets (ITNs) on drug resistance …

Background: Antimalarial drug resistance is a major obstacle to sustainable malaria control.
Here we use amplicon sequencing to describe molecular markers of drug resistance in …

Background Since the late 1980s a series of malaria epidemics has occurred in western
Kenya highlands. Among the possible factors that may contribute to the highland malaria …

Resistance to the mainstay antimalarial drugs is a major concern in the control of malaria.
Delayed Plasmodium falciparum parasite clearance has been associated with Single …