In our grim global village, every other human being is exposed to malaria. This sad figure
grows and grows. 1 Each year, 1–3 million people die from malaria, mostly aged under 5 …

are exciting and show clearly a protective effect against severe malaria and delays in the
time to a first attack of clinical malaria and to the appearance of parasites in the blood after …

Large gains in the reduction of malaria mortality in the early 20th century were lost in
subsequent decades. Malaria now kills 2–3 million people yearly. Implementation of malaria …

Malaria is still killing over one million people each year and its incidence is increasing. The
need for an effective vaccine is greater than ever. A major difficulty with vaccine research is …

Two recent studies by Philip Bejon1 and Salim Abdulla, 2 and their respective colleagues,
represent an important step towards the development of a malaria vaccine that shows great …

An unexpectedly large reduction in the burden of malaria has recently been achieved in a
number of malaria endemic countries following the scaling up of effective treatment and …

In October 2006, the World Health Organisation (WHO) convened a meeting of experts to
discuss appropriate methods for evaluating the efficacy of malaria vaccines in pivotal phase …

Major technical advances in the field of vaccine development have culminated in an
impressive array of prototype vaccines that may well provide'proof of principle'that vaccines …

Background The efficacy of RTS, S/AS01 as a vaccine for malaria is being tested in a phase
3 clinical trial. Early results show significant, albeit partial, protection against clinical malaria …

Studies and trials in the field are key to the development of a vaccine for malaria. Our limited
knowledge of naturally acquired immunity and of transmission dynamics and disease …