Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options

S Ulusoy, G Ozkan, M Alkanat, S Mungan… - American journal of …, 2013 - karger.com
Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …

[HTML][HTML] Differences in gene expression profiles and signaling pathways in rhabdomyolysis-induced acute kidney injury

X Geng, Y Wang, Q Hong, J Yang… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Purpose: Rhabdomyolysis is a threatening syndrome because it causes the breakdown of
skeletal muscle. Muscle destruction leads to the release of myoglobin, intracellular proteins …

Risk factors for severe acute kidney injury among patients with rhabdomyolysis

J Yang, J Zhou, X Wang, S Wang, Y Tang, L Yang - BMC nephrology, 2020 - Springer
Background Acute kidney injury (AKI) is a life-threatening complication of rhabdomyolysis
(RM). The aim of the present study was to assess patients at high risk for the occurrence of …

The value of serum creatine kinase in predicting the risk of rhabdomyolysis-induced acute kidney injury: a systematic review and meta-analysis

S Safari, M Yousefifard, B Hashemi, A Baratloo… - Clinical and …, 2016 - Springer
Introduction Identifying the potential effective factors of rhabdomyolysis-induced acute
kidney injury (AKI) is of major importance for both treatment and logistic concerns. The …

Rhabdomyolysis

SD Bieber, JA Jefferson - Nephrology Secrets, 2012 - Elsevier
Rhabdomyolysis is a condition characterized by muscle injury leading to myocyte necrosis
with the subsequent release of toxic intracellular contents into the circulation. The term is …

Acute kidney injury due to rhabdomyolysis

RSA Lima, GB da Silva Junior, AB Liborio… - Saudi journal of …, 2008 - journals.lww.com
Rhabdomyolysis is a clinical and biochemical syndrome that occurs when skeletal muscle
cells disrupt and release creatine phosphokinase (CK), lactate dehydrogenase (LDH), and …

[HTML][HTML] Causes and outcome of rhabdomyolysis in patients admitted to medical wards in the Prince of Wales Hospital

W Zeng, B Tomlinson - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Background Rhabdomyolysis with a marked elevation of serum creatine kinase (CK) can be
caused by various conditions. Acute kidney injury (AKI) is a potential complication of severe …

Rhabdomyolysis: a 10-year retrospective study of patients treated in a medical department

M Vangstad, MA Bjornaas… - European Journal of …, 2019 - journals.lww.com
Background Rhabdomyolysis is a common and potentially life-threatening syndrome, and
acute kidney injury (AKI) is a serious complication. We performed a 10-year retrospective …

Risk factors for acute kidney injury in severe rhabdomyolysis

E Rodríguez, MJ Soler, O Rap, C Barrios, MA Orfila… - PloS one, 2013 - journals.plos.org
Background Acute kidney injury (AKI) is a life-threatening complication of severe
rhabdomyolysis. This study was conducted to assess risk factors for AKI and to develop a …

Molecular mechanisms of rhabdomyolysis-induced kidney injury: from bench to bedside

JF Hebert, KG Burfeind, D Malinoski… - Kidney International …, 2023 - Elsevier
Rhabdomyolysis-induced acute kidney injury (RIAKI) occurs following damage to the
muscular sarcolemma sheath, resulting in the leakage of myoglobin and other metabolites …