Spinal cord injury (SCI) results in motor and sensory deficits, the severity of which depends
on the level and extent of the injury. Animal models for SCI research include transection …

Endogenous cell proliferation and gliogenesis have been extensively documented in spinal
cord injury, particularly in terms of proliferating oligodendrocyte progenitor cells. Despite the …

Every year, 0.93 million people worldwide suffer from spinal cord injury (SCI) with
irretrievable sequelae. Rehabilitation, currently the only available treatment, does not …

Harnessing the regenerative capabilities of endogenous precursor cells in the spinal cord
may be a useful tool for clinical treatments aimed at replacing cells lost as a consequence of …

As our understanding and ability to direct the differentiation of stem cells grows, specific
targets and strategies to incorporate them are essential to define. Any cell-based …

Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The
incidence of SCI keeps increasing, resulting in huge burden on the society. The …

Neural stem cells (NSCs) expressing GFP were embedded into fibrin matrices containing
growth factor cocktails and grafted to sites of severe spinal cord injury. Grafted cells …

✓ The development of an acute traumatic spinal cord injury (SCI) inevitably leads to a
complex cascade of ischemia and inflammation that results in significant scar tissue …

Ependymal cells, a dormant population of ciliated progenitors found within the central canal
of the spinal cord, undergo significant alterations after spinal cord injury (SCI) …

This article reviews stem cell-based strategies for spinal cord injury repair, and practical
issues concerning their translation to the clinic. Recent progress in the stem cell field …