With the nearly simultaneous development of prostate-specific antigen (PSA), the automated
biopsy" gun," and a public interest in the early detection of prostate cancer, the number of …

The optimal treatment of the patient at high risk for local recurrence of prostate cancer after
radical prostatectomy is controversial. Similarly, there is much controversy over how to treat …

Radiation therapy, either external beam irradiation or brachytherapy, remains a popular
therapeutic modality for clinically organ-confined (stages T1 and T2) or locally invasive …

PURPOSE: In patients treated with radical prostatectomy in the prostate-specific antigen
(PSA) era, it has been demonstrated that the year of treatment in the PSA era is associated …

OBJECTIVES: Men with clinically detected localized prostate cancer treated without curative
intent are at risk of complications from local tumor growth. We investigated rates of local …

When discussing the place for surveillance in the treatment of localized prostate cancer,
several questions have to be answered. First of all, we must ask, does prostate cancer …

We agree with Klotz and Kibel that the lack of significant differences in survival among the
three treatments makes a comparison between radiotherapy and surgery unwise. The …

Purpose: Because data from randomized trials initiated after the introduction of prostate
specific antigen testing are unavailable, we performed a retrospective, population based …

Critics of screening have stated that early detection of prostate cancer does not necessarily
reflect a diminishing death rate from the disease. However, several recent reports have …

CONTEXT: The appropriate therapy for men with clinically localized prostate cancer is
uncertain. A recent study suggested an increasing prostate cancer mortality rate for men …