Background To examine the association of increased plasma leptin concentration with
prevalent stroke and coronary heart disease (CHD) and to examine the genetic contributions …

Leptin, an adipose tissue–derived hormone, has been linked to cardiovascular outcomes;
however, data are limited in the United States population, especially women. To assess the …

Background and purpose Although high leptin concentration has been shown to be
correlated with established vascular risk factors, epidemiologic studies have reported …

Objective: Prospective studies have shown a positive association between leptin
concentrations and coronary heart disease (CHD) in men, but its effect in women is unclear …

Objective Higher serum leptin levels have been associated with a modestly higher incidence
of cardiovascular disease in studies involving mostly Caucasian men. We aimed to assess …

Background—Leptin plays a role in fat metabolism and correlates with insulin resistance
and other markers of the metabolic syndrome, independent of total adiposity. Therefore, we …

Objectives: This study sought to better determine the link between leptin and coronary heart
disease (CHD). Background: Circulating leptin is considered a risk factor for CHD but larger …

Background New and clinically useful markers of cardiovascular risk are of essence in type
2 diabetes since ischemic heart disease is a major cause of death in these patients …

Objective This meta-analysis aimed to investigate the association of leptin levels with
pathogenetic risk of CHD and stroke. Materials and methods Studies were identified in the …

Background and Purpose—Leptin is a major adipokine that regulates weight balance and
energy homeostasis. There is inconsistent evidence linking circulating leptin levels to risk of …