BACKGROUND: The sympathetic nervous system has a unique role in endothelial function,
and beta-receptors are a key part of sympathetic nervous system function. OBJECTIVE: To …

Objectives To compare the effects of nebivolol and atenolol in 25 ambulatory hypertensive
patients with impaired glucose tolerance. Design Clinic and ambulatory blood pressure …

Essential hypertension is associated with impaired endothelium-dependent vasodilation
and is caused mainly by production of oxygen free radicals that can destroy nitric oxide …

Aims/hypothesis Impaired nitric oxide (NO) bioactivity and increased superoxide (SO)
production are characteristics of vascular endothelial dysfunction in diabetes. The …

Micro‐and macrovascular complications are the leading causes of mortality in Types I and II
diabetes. Hyperglycemia results in increased advanced glycosylation end (AGE) products …

Purpose: Nebivolol is a highly selective β1-adrenoceptor blocker with additional
vasodilating properties. It has been shown that the nebivolol-induced vasorelaxation is nitric …

Background—Nebivolol is a β1-selective adrenergic receptor antagonist with proposed nitric
oxide (NO)–mediated vasodilating properties in humans. In this study, we explored whether …

Endothelial dysfunction is considered as a major risk factor of cardiovascular complications
of type I and types II diabetes. Impaired endothelium-dependent vasodilatation can be …

The aim of this double-blind, parallel group study was to compare the effects of nebivolol
and atenolol on blood pressure (BP) and insulin sensitivity in hypertensive patients with type …

Nebivolol is a highly selective β 1-adrenoreceptor-blocking agent with a peculiar
pharmacodynamic profile. It has peripheral acute vasodilating properties that are mediated …