Microvascular and macrovascular complications are major causes of disability and death in
diabetic patients. High levels of blood glucose sabotage the integrity of blood vessels and …

In this multicenter trial, the effects of nebivolol added to an angiotensin‐converting enzyme
(ACE) inhibitor or angiotensin II receptor blocker (ARB) were assessed in patients with …

Background: Data suggest that carvedilol possesses antioxidant properties that might
provide vascular protection. We sought to compare the effects of carvedilol and metoprolol …

Background Impairment of endothelium-dependent vasorelaxation has been suggested to
play a principle role of endothelial dysfunction in the development of cardiovascular …

Nebivolol, a racemic mixture of (S, R, R, R) and (R, S, S, S) enantiomers, is the most β 1-
selective adrenoceptor antagonist currently available for clinical use. However, its …

Objectives: The objective of the present study was to elucidate the vasodilator mechanisms
of nebivolol, a high selective β1-receptor antagonist with antioxidant properties …

Objective To obtain further insight into the mechanism underlying the vasodilator effect of
nebivolol. Since oxidative inactivation of nitric oxide (NO) is regarded as an important cause …

Background Nicorandil, an anti-angina agent, reportedly improves outcomes even in angina
patients with diabetes. However, the precise mechanism underlying the beneficial effect of …

Aim: The aim of this study was to examine the effect of the cadioselective B1‐adrenoceptor
blocker nebivolol on glycaemic control, lipid profile and markers of oxidative stress in …

Patients with diabetes mellitus (DM) have a high prevalence of coronary artery disease
(CAD), as diabetes is implicated in the formation of atherosclerotic plaque. Endothelial …