Early effects of treatment with nebivolol and quinapril on endothelial function in patients with hypertension

H Korkmaz, I Karaca, M Koç, O Önalan, M Yilmaz… - Endothelium, 2008 - Taylor & Francis
The objective of the present study was to compare the early effects of treatment with
nebivolol and quinapril on the endothelial function in hypertensive patients. A total of 54 …

Effect of nebivolol on renal nitric oxide availability and tubular function in patients with essential hypertension

FH Mose, JM Jensen, S Therwani… - British Journal of …, 2015 - Wiley Online Library
Aims Nebivolol is a selective β1‐receptor antagonist with vasodilating properties. In patients
with essential hypertension, we tested the hypothesis that nebivolol increases systemic and …

Use of nebivolol for the treatment of endothelial dysfunction in patients with hypertension: the EDEN registry

O Masoli, M Redruello, NP Baliño… - Journal of …, 2008 - journals.lww.com
This aim of this study was to evaluate the presence of endothelial dysfunction in patients
with primary hypertension and to determine the usefulness of nebivolol, a selective β …

The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin–induced diabetic rats is restored by 5 …

AS De Vriese, J Van de Voorde, HJ Blom… - Diabetologia, 2000 - Springer
Aims/hypothesis. Endothelial dysfunction contributes to the development of diabetic vascular
complications. A better understanding of the pathophysiology of endothelial dysfunction in …

Nebivolol alleviates aortic remodeling through eNOS upregulation and inhibition of oxidative stress in l-NAME-induced hypertensive rats

Y Wang, F Zhang, Y Liu, S Yin, X Pang… - Clinical and …, 2017 - Taylor & Francis
Purpose: To investigate the effect and mechanism of nebivolol on aortic remodeling in N-
nitro-l-arginine methyl ester (l-NAME)-induced hypertension. Methods: Male Sprague …

Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II …

NC Moningka, T Tsarova, JM Sasser… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. Nitric oxide (NO) deficiency contributes to chronic kidney disease (CKD)
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …

[HTML][HTML] Enhancement of endothelial nitric oxide synthase production reverses vascular dysfunction and inflammation in the hindlimbs of a rat model of diabetes

A Riad, D Westermann, S Van Linthout, Z Mohr… - Diabetologia, 2008 - Springer
Aims/hypothesis Reduced bioavailability of nitric oxide (NO) is a hallmark of diabetes
mellitus-induced vascular complications. In the present study we investigated whether a …

Targeting endothelial dysfunction in hypertensive subjects

C Thuillez, V Richard - Journal of human hypertension, 2005 - nature.com
The endothelium is a favourite early target of cardiovascular risk factors and cardiovascular
diseases like hypertension. This key role of the endothelium results from its capacity to …

Malfunction of vascular control in lifestyle-related diseases: mechanisms underlying endothelial dysfunction in the insulin-resistant state

K Shinozaki, K Ayajiki, A Kashiwagi… - Journal of …, 2004 - jstage.jst.go.jp
It is tempting to speculate that increased vasoconstriction and loss of endotheliumdependent
vasodilation might be etiological factors of elevated blood pressure in the insulinresistant …

Nebivolol increases arterial distensibility in vivo

CM McEniery, M Schmitt, A Qasem, DJ Webb… - …, 2004 - Am Heart Assoc
Arterial stiffness is a key determinant of cardiovascular risk in hypertensive patients. β-
Blockers appear to be less effective than other drugs in improving outcome in hypertensive …