Brainstem neuroimaging of nociception and pain circuitries

V Napadow, R Sclocco, LA Henderson - Pain Reports, 2019 - journals.lww.com
The brainstem is known to be an important brain area for nociception and pain processing,
and both relaying and coordinating signaling between the cerebrum, cerebellum, and spinal …

From nociception to pain perception: imaging the spinal and supraspinal pathways

J Brooks, I Tracey - Journal of anatomy, 2005 - Wiley Online Library
Functional imaging techniques have allowed researchers to look within the brain, and
revealed the cortical representation of pain. Initial experiments, performed in the early …

Imaging acute and chronic pain in the human brainstem and spinal cord

LA Henderson, KA Keay - The Neuroscientist, 2018 - journals.sagepub.com
While acute pain serves as a protective mechanism designed to warn an individual of
potential or actual damaging stimuli, chronic pain provides no benefit and is now considered …

Neuroimaging mechanisms in pain: from discovery to translation

I Tracey - Pain, 2017 - journals.lww.com
Several reviews comprehensively cover many of the amazing developments surrounding
how pain as a perceptual experience is understood using neuroimaging. These, to a greater …

Neuroimaging enters the pain biomarker arena

I Tracey - Science translational medicine, 2021 - science.org
Neuroimaging enters the pain biomarker arena | Science Translational Medicine news careers
commentary Journals Science Science brought to you byGoogle Indexer Log in science …

Brainstem pain-modulation circuitry and its plasticity in neuropathic pain: insights from human brain imaging investigations

EP Mills, KA Keay, LA Henderson - Frontiers in Pain Research, 2021 - frontiersin.org
Acute pain serves as a protective mechanism that alerts us to potential tissue damage and
drives a behavioural response that removes us from danger. The neural circuitry critical for …

Imaging CNS modulation of pain in humans

U Bingel, I Tracey - Physiology, 2008 - journals.physiology.org
Pain is a highly complex and subjective experience that is not linearly related to the
nociceptive input. What is clear from anecdotal reports over the centuries and more recently …

Pain networks from the inside: spatiotemporal analysis of brain responses leading from nociception to conscious perception

H Bastuji, M Frot, C Perchet, M Magnin… - Human brain …, 2016 - Wiley Online Library
Conscious perception of painful stimuli needs the contribution of an extensive cortico‐
subcortical network, and is completed in less than one second. While initial activities in …

[HTML][HTML] Distinguishing pain from nociception, salience, and arousal: how autonomic nervous system activity can improve neuroimaging tests of specificity

IS Lee, EA Necka, LY Atlas - Neuroimage, 2020 - Elsevier
Pain is a subjective, multidimensional experience that is distinct from nociception. A large
body of work has focused on whether pain processing is supported by specific, dedicated …

Imaging pain modulation in health and disease

U Bingel, E Schoell, C Büchel - Current opinion in neurology, 2007 - journals.lww.com
Top-down pain modulation relies on both cortical and subcortical structures. Research on
the involved circuitry, including the implemented mechanisms, is a major focus of …