Introduction The transformation of acute myeloid leukemia with translocation (16; 16)(p13;
q22) from AML M2 to acute monocytic leukemia (AML M5) during therapy is a rare clinical …

Objectives Acute myeloid leukemia (AML) with t (8; 16)(p11; p13) abnormalities is a rare,
aggressive, and diagnostically challenging subtype that results in KAT6A-CREBBP gene …

Abstract Translocation t (6; 9) is a rare cytogenetic abnormality found in fewer than 5% of
pediatric and adult cases of acute myelogenous leukemia (AML). The outcomes of t (6; 9) …

We present a novel, rare but recurrent variant three way translocation of t (8; 21), t (8; 16;
21)(q22; q24; q22), as a primary cytogenetic abnormality, resulting in AML1/ETO fusion …

The classification of acute myeloid leukemia (AML) recognizes a subgroup of diseases with
recurring genetic abnormalities. Translocation (15; 17) is the marker of acute promyelocitic …

Six patients with de novo acute myeloid leukemia (AML) and at (2; 3)(p15–21; q26–27) were
identified among approximately 1000 cases enrolled in the GIMEMA trial. The t (2; 3) was …

Abstract The translocation (8; 21)(q22; q22) is associated with acute myeloblastic leukemia
(AML) with M2 subtype. The accurate detection of this chromosomal rearrangement is vital …

Chromosome 21 and in particular band 21q22, the site of AML1 (RUNX1, CBFA2) gene, is
among the most frequent targets of chromosomal translocations in leukemia observed in …

Cytogenetic abnormalities play an important role in diagnosis, classification and prognosis
in acute myeloid leukemia (AML). Nevertheless, several chromosome abnormalities have …

The cellular and molecular genetic aberrations of hematopoietic and lymphoid tissues are
increasingly important in leukemia classification and are prognostically significant. Although …