AML with translocation t (3; 5) belongs to the “AML with myelodysplasia-related changes”
defined in the 2008 WHO classification. 1 The incidence of this balanced abnormality is less …

Objectives: Translocation (8; 21) is a RUNX1-RUNX1T1 fusion transcript, a favorable risk
cytogenetic abnormality with a variable clinicopathological profile. However, there is a …

Introduction: Allogeneic stem cell transplantation (allo-SCT) is the best post-remission
treatment for patients (pts) with acute myeloid leukemia (AML) harboring high-risk genetic …

Abstract Abstract 1456 Background: Cytogenetic analysis of large pt cohorts allows us to
evaluate the prognostic impact of rare and unique translocations. Little is known about the …

Acute myeloid leukemia with maturation (AML-M2) is associated with the 8; 21 translocation.
For the first time in an adult patient with AML-M2, a novel unbalanced translocation involving …

Acute myeloid leukaemia (AML) is a type of heterogeneous disease derived from
haematopoietic stem cells. Cytogenetic characterisation is essential for diagnosis and …

Background: Acute myeloid leukemia (AML) is a heterogeneous group of malignant
neoplasm of hematopoietic disorders characterized by an abnormal proliferation of myeloid …

Background: t (8; 21)(q22; q22) is the most frequent recurrent translocation in acute myeloid
leukemia (AML) resulting in an in-frame fusion of RUNX1/RUNX1T1 that regulates various …

Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow. It is the most
common type of acute leukemia in adults. This type of cancer usually gets worse quickly if it …

Abstract The t (1; 11)(p32; q23) translocation is a rare but recurrent cytogenetic aberration in
acute myeloid leukemia (AML) and B-cell acute lymphoblastic leukemia (B-ALL). This …