Nature has evolved multiple enzymatic strategies for the degradation of plant cell wall
polysaccharides, which are central to carbon flux in the biosphere and an integral part of …

Cellulose, the main structural component of plant cell walls, is the most abundant
carbohydrate polymer in nature. Although abundant, it is extremely difficult to degrade, as it …

Highlights•Cellulosome complexes mediate efficient hydrolysis of plant-derived
polysaccharides.•Computational biology reveals structure-function relationships of …

Cellulose is the most abundant biopolymer and a major reservoir of fixed carbon on earth.
Comprehension of the elusive mechanism of its enzymatic degradation represents a …

Enzyme catalyzed conversion of plant biomass to sugars is an inherently inefficient process,
and one of the major factors limiting economical biofuel production. This is due to the …

Efficient breakdown of lignocellulose polymers into simple molecules is a key technological
bottleneck limiting the production of plant-derived biofuels and chemicals. In nature, plant …

Background The concerted action of three complementary cellulases from Clostridium
thermocellum, engineered to be stable at elevated temperatures, was examined on a …

The cellulosome is a supramolecular multienzyme complex comprised of a wide variety of
polysaccharide-degrading enzymes and scaffold proteins. The cellulosomal enzymes that …

▪ Abstract The discrete multicomponent, multienzyme cellulosome complex of anaerobic
cellulolytic bacteria provides enhanced synergistic activity among the different resident …

Despite its simple chemical composition, cellulose exists in a number of crystalline and
amorphous topologies. Its insolubility and heterogeneity makes native cellulose a …