Phospholipid scramblase 1 potentiates the antiviral activity of interferon

B Dong, Q Zhou, J Zhao, A Zhou, RN Harty… - Journal of …, 2004 - Am Soc Microbiol
ABSTRACT Phospholipid scramblase 1 (PLSCR1) is an interferon (IFN)-and growth factor-
inducible, calcium-binding protein that either inserts into the plasma membrane or binds …

Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells

Y Huang, Q Zhao, CX Zhou, ZM Gu, D Li, HZ Xu… - Oncogene, 2006 - nature.com
Abstract Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated protein which is
localized in either the cell membrane or nucleus depending on its palmitoylated state. The …

[HTML][HTML] Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor

M Nanjundan, J Sun, J Zhao, Q Zhou, PJ Sims… - Journal of Biological …, 2003 - ASBMB
Phospholipid scramblase (PLSCR1) is a multiply palmitoylated, calcium-binding endofacial
membrane protein proposed to mediate transbilayer movement of plasma membrane …

Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response

B Lu, PJ Sims, T Wiedmer, AH Moser… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Phospholipid scramblase 1 (PLSCR1) is a member of PLSCR gene family that has been
implicated in multiple cellular processes including movement of phospholipids, gene …

[HTML][HTML] The role of human phospholipid scramblases in apoptosis: An overview

U Sivagnanam, SK Palanirajan… - Biochimica et Biophysica …, 2017 - Elsevier
Human phospholipid scramblases (hPLSCRs) are a family of four homologous single pass
transmembrane proteins (hPLSCR1-4) initially identified as the proteins responsible for Ca …

The single C‐terminal helix of human phospholipid scramblase 1 is required for membrane insertion and scrambling activity

VG Francis, AM Mohammed, GK Aradhyam… - The FEBS …, 2013 - Wiley Online Library
Human phospholipid scramblase 1 (hPLSCR 1) belongs to the ATP‐independent class of
phospholipid translocators which possess a single EF‐hand‐like Ca2+‐binding motif and …

[HTML][HTML] c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1

J Sun, J Zhao, MA Schwartz, JYJ Wang… - Journal of Biological …, 2001 - ASBMB
Phospholipid scramblase 1 (PLSCR1) is a plasma membrane protein that has been
proposed to play a role in the transbilayer movement of plasma membrane phospholipids …

Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3)

T Wiedmer, J Zhao, L Li, Q Zhou… - Proceedings of the …, 2004 - National Acad Sciences
The phospholipid scramblases (PLSCR1 to PLSCR4) are a structurally and functionally
unique class of proteins, which are products of a tetrad of genes conserved from …

Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1

Q Zhou, J Zhao, T Wiedmer… - Blood, The Journal of the …, 2002 - ashpublications.org
Phospholipid scramblase 1 (PLSCR1) is an endofacial plasma membrane protein proposed
to participate in transbilayer movement of phosphatidylserine and other phospholipids. In …

Over-expression of recombinant human phospholipid scramblase 1 in E. coli and its purification from inclusion bodies

SK Sahu, A Gopala Krishna, SN Gummadi - Biotechnology letters, 2008 - Springer
Abstract Human phospholipid scramblase 1 (hPLSCR1) scrambles plasma membrane
phospholipids during cell activation, blood coagulation and apoptosis. It was over …