Neither blood culture positivity nor time to positivity is associated with mortality among patients presenting with severe manifestations of sepsis: the FABLED cohort …

K Paquette, D Sweet, R Stenstrom… - Open Forum …, 2021 - academic.oup.com
Background Sepsis is a leading cause of morbidity, mortality, and health care costs
worldwide. Methods We conducted a multicenter, prospective cohort study evaluating the …

[HTML][HTML] Comparing mortality between positive and negative blood culture results: an inverse probability of treatment weighting analysis of a multicenter cohort

A Liu, CH Yo, L Nie, H Yu, K Wu, HS Tong… - BMC Infectious …, 2021 - Springer
Background The association between blood culture status and mortality among sepsis
patients remains controversial hence we conducted a tri-center retrospective cohort study to …

[HTML][HTML] Impact of antibiotic administration on blood culture positivity at the beginning of sepsis: a prospective clinical cohort study

CS Scheer, C Fuchs, M Gründling, M Vollmer… - Clinical Microbiology …, 2019 - Elsevier
Objectives Sepsis guidelines recommend obtaining blood cultures before starting anti-
infective therapy in patients with sepsis. However, little is known of how antibiotic treatment …

Comparison of length of stay and outcomes of patients with positive versus negative blood culture results

D Armstrong-Briley, NST Hozhabri… - Baylor University …, 2015 - Taylor & Francis
In the United States, sepsis is the leading cause of death in critically ill patients. The fatality
rate for severe sepsis is about 40%, and treatment costs over $16 billion annually. It is …

[HTML][HTML] Initial levels of organ failure, microbial findings and mortality in intensive care-treated primary, secondary and tertiary sepsis

M Castegren, M Jonasson, S Castegren… - Critical Care and …, 2015 - Elsevier
Objective: Analysis of whether patients with primary, secondary and tertiary sepsis, defined
by the presence or absence of recent systemic inflammation-inducing events before the …

Blood culture results before and after antimicrobial administration in patients with severe manifestations of sepsis: a diagnostic study

MP Cheng, R Stenstrom, K Paquette… - Annals of internal …, 2019 - acpjournals.org
Background: Administering antimicrobial agents before obtaining blood cultures could
potentially decrease time to treatment and improve outcomes, but it is unclear how this …

[HTML][HTML] Sepsis-related mortality in 497 cases with blood culture-positive sepsis in an emergency department

J Rannikko, J Syrjänen, T Seiskari, J Aittoniemi… - International Journal of …, 2017 - Elsevier
Objective Few studies have sought to establish how often death after sepsis is related to the
sepsis and how often underlying diseases have a major role in case fatality. Methods In this …

Real-world time to positivity of 2 widely used commercial blood culture systems in patients with severe manifestations of sepsis: an analysis of the FABLED study

G Butler-Laporte, CP Yansouni… - Open Forum …, 2020 - academic.oup.com
Background Of all microbiological tests performed, blood cultures have the most impact on
patient care. Timely results are essential, especially in the management of sepsis. While …

Positive culture and prognosis in patients with sepsis: a prospective cohort study

F Molina, P Castaño, M Plaza… - Journal of Intensive …, 2020 - journals.sagepub.com
Purpose: To analyze the prognostic role of positive cultures in patients with sepsis. Methods:
A prospective cohort study in a tertiary referral hospital in Medellín, Colombia. Adults older …

[HTML][HTML] Bacteremic sepsis leads to higher mortality when adjusting for confounders with propensity score matching

L Mellhammar, F Kahn, C Whitlow, T Kander… - Scientific reports, 2021 - nature.com
One can falsely assume that it is well known that bacteremia is associated with higher
mortality in sepsis. Only a handful of studies specifically focus on the comparison of culture …