[PDF][PDF] Timing and spectrum of antibiotic treatment for suspected sepsis and septic shock: why so controversial?

TR Pak, C Rhee, M Klompas - Infectious Disease Clinics of North America, 2022 - Elsevier
Background Sepsis, defined as a dysregulated host response to infection leading to acute
organ dysfunction, affects millions of patients per year. It is associated with 850,000 visits to …

Timing and appropriateness of initial antibiotic therapy in newly presenting septic patients

AL Vilella, CF Seifert - The American journal of emergency medicine, 2014 - Elsevier
Objective To determine the effectiveness of antibiotic regimens and time to antibiotics in
septic patients admitted to an intensive care unit from the emergency department. Methods A …

[HTML][HTML] Factors affecting the time to first dose antibiotic in sepsis in acute emergency

JV Joseph, M Madhiyazhagan, R Roshan… - Indian Journal of …, 2021 - ncbi.nlm.nih.gov
Background The Surviving Sepsis Campaign recommends the administration of antibiotics
within 1 hour of triage time in sepsis patients. The purpose of this study was to determine the …

Early ICU-mortality in sepsis–causes, influencing factors and variability in clinical judgement: a retrospective cohort study

RGH Driessen, NFL Heijnen, RPMG Hulsewe… - Infectious …, 2021 - Taylor & Francis
Background Sepsis is a global health care problem with a high mortality. Early death seems
common; however, data are sparse. The objective of the present study was to report causes …

Biomarkers of early sepsis may be correlated with outcome

TH Hong, CH Chang, WJ Ko, CF Lin, HH Liu… - Journal of Translational …, 2014 - Springer
Background Sepsis causes high mortality, and the mortality due to secondary infections is
even higher. No studies to date have investigated the time from the primary infection to …

The puzzle of sepsis: fitting the pieces of the inflammatory response with treatment

J Cunneen, M Cartwright - AACN Advanced Critical Care, 2004 - AACN
Sepsis is a complex syndrome characterized by simultaneous activation of inflammation and
coagulation in response to microbial insult. These events manifest as systemic inflammatory …

Prospective observational study comparing sepsis-2 and sepsis-3 definitions in predicting mortality in critically ill patients

DD Poutsiaka, MC Porto, WA Perry… - Open forum …, 2019 - academic.oup.com
Background Sepsis definitions have evolved, but there is a lack of consensus over adoption
of the most recent definition, Sepsis-3. We sought to compare Sepsis-2 and Sepsis-3 in the …

Correction: Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public …

CP Kovach, GS Fletcher, KE Rudd, RM Grant… - Plos one, 2019 - journals.plos.org
The word" populations" is missing from the article title. The correct title is: Comparative
prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection …

Risk factors for readmission after sepsis and its association with mortality

M Engoren, C Arslanian-Engoren - Heart & Lung, 2024 - Elsevier
Background Sepsis is associated with an approximately 20% 30-day readmission rate and
with subsequent mortality. Objectives To determine the demographics, comorbidities that …

Correction: Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study

G Husabø, RM Nilsen, H Flaatten, E Solligård, JC Frich… - Plos one, 2021 - journals.plos.org
There is an error in the caption for Fig 2,“All-cause 30-day mortality by time to antibiotic
treatment.” Date of admission was not measured using calendar days and it was not entered …