OBJECTIVES Irritable bowel syndrome (IBS) is a heterogeneous condition and defined
according to symptoms. Low-grade inflammation has been associated with IBS, particularly …

Background Alterations in gastrointestinal (GI) permeability and immune measures are
present in some patients with irritable bowel syndrome (IBS) but the relationship to …

Background/Aims: Defective epithelial barrier has been implicated in the pathogenesis of
irritable bowel syndrome (IBS) and inflammatory bowel diseases. The aim of this study was …

Background: Post‐infectious irritable bowel syndrome is a common clinical phenomenon of
uncertain aetiology. Aim: To test the association between intestinal permeability and irritable …

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder in which the underlying
pathophysiology is poorly understood; however, increased intestinal permeability in …

Based on a systematic PubMed search, this short review addresses why intestinal
permeability may be important in the pathobiology of irritable bowel syndrome (IBS), the …

There has been recent interest into the potential role of cellular and molecular mechanisms
in the pathophysiology of irritable bowel syndrome (IBS). Although the intestinal mucosa of …

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal ailments among
those seeking health care for gastrointestinal disorders. Despite its prevalence, IBS …

Background Intestinal permeability has been studied in small groups of IBS patients with
contrasting findings. Aims To assess intestinal permeability at different sites of the GI tract in …

OBJECTIVES: Recent evidence suggests a role for increased colonic permeability and
mucosal mast cell (MC) mediators on symptoms related to the irritable bowel syndrome …